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不育症的精液检验与血清中AsAb的关系 被引量:6

Relationship between Evaluation on Semen and Anti-sperm Antibody of Serum in Infertile Men
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摘要 目的 对194例男性不育症患者进行精液常规检验和血清中抗精子抗体(AsAb)检测,并进行相关比较。方法 对194例男性不育症患者进行精子密度、精子活动力、精子活动百分率、精子中的白细胞、精子的液化时间、精液量、pH值等常规检验,同时用放免法对血清中的AsAb进行检测。结果精子的密度(20—100)×10^9/L,AsAb的阳性率77.8%~10.0%;精子活动力良好到无精,AsAb的阳性率15.9%-77.8%;精子活动的百分率80%以上到10%以下,AsAb阳性率11.5%-80.0%。精子中白细胞数量越多,AsAb阳性率越高。而精液量、液化时间、精液酸碱度与AsAb的阳性率无关。结论 不育症患者其精液中AsAb阳性率的高低对精子密度、精子活动力、精子活动百分率产生很大的影响,测定AsAb对查找男性不育症患者的病因有很重要的临床价值。 Objective To explore the relationship between the result of routine semen detection and anti-sperm antibody(As- Ab) of serum in the infertile men. Methods 194 cases of infertility were selected and the semen item which include sperm density, sperm motility,percentage of sperm motility,pH,WBC in semen,liquefaction time and quantity of semen were tested by routine laboratory methods and the AsAb in serum were detected by radioimmunoassay. Results The rang of positive rate of AsAb were 77.8% to 10%, 11.5% to 80% and 15.9 to 77.8% when the sperm density,percentage of sperm motility and activity rate of sperm were 20 × 10^9/L to 100 ×10^9/L,80% to 10% and C to A respectively. The number of WBC in semen directly related to the positive rate of AsAb, while the liquefaction time and quantity of semen and pH did not. Conclusions The influence of AsAb positive rate in serum on the sperm density ,the sperm motility ,the percentage of sperm motility was distinctly. The evaluation of serum AsAb is of higher clinical value in the diagnosis of infertility.
作者 陈丹
出处 《实用全科医学》 2007年第9期827-828,共2页 Applied Journal Of General Practice
关键词 不育症 精液 精子密度 精子活动力 精子活动百分率 抗精子抗体 Infertility Semen Sperm density Sperm motility Sperm activity rate Anti-sperm antibody
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  • 1梁业丽,李海生,张飞凌.抗精子抗体与抗子宫内膜抗体在女性不孕中的检测价值[J].中国妇幼保健,2005,20(8):932-934. 被引量:9
  • 2王士娴,李大勤.免疫性不育的诊断方法:微量抗精子抗体测定及其临床应用[J].中华医学检验杂志,1989,12(4):209-211. 被引量:4
  • 3傅广波,钱立新,崔毓桂.男性自身抗精子抗体的临床研究[J].国外医学(计划生育分册),2005,24(6):317-321. 被引量:14
  • 4[1]MORETTA A.Major histocompatibility complex class I-specific receptors on human natural killer and T Lymphocytes[J].Immund Rev,1997,155:105.
  • 5[4]MATHURS,ROSENLUND C,CARLTON METALl.Studies on sperm survial and mobility In the persencre of cytotoxic sperm antibodies[J].Am J Repro Immunol,1988,17:41.
  • 6[5]TUMG K S K,OKADA A,YANAGIMACHI R.Sperm auto-antigens and fertilization l.Effects of antibodies on rouleaux formation.Viability and acrosome reactive of guinea pig sperm[J].Biol Repro.1980,23:877.
  • 7[7]CIATKE C N,HYNE R V.Sperm antibodies and human in aiarofertilization[J].Fertil Steril.1988,49(6):10-18.
  • 8Allegrucci C,Ronquist G,Ove Nilsson B,et al.Am J Reprod Immunol 2001; 46(3):211-219
  • 9Chiu WWC,Chamley LWC.Hum Reprod 2002; 17:984-989
  • 10Bohring C,Krause W.Am J Reprod Immunol 2003; 50(5):411-419

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