摘要
目的评价近视眼患者长期配戴角膜塑形镜对角膜厚度和角膜内皮细胞的影响。方法利用超声角膜测厚仪和非接触角膜内皮显微镜，测量和观察132名青少年近视眼患者（264只眼）配戴角膜塑形镜（透氧系数为100）前和戴镜期间的角膜中央和旁周边部的角膜厚度，以及角膜内皮细胞的密度和形态学改变。结果无论采用夜戴方式还是日戴方式配戴角膜塑形镜3年以上，角膜中央及旁周边部厚度均无明显改变（P〉0．05），角膜内皮细胞密度均无明显降低（P〉0．05），角膜内皮细胞平均面积和细胞变异系数均无明显增大（P〉0．05），角膜内皮细胞六角形比率均无明显降低（P〉0．05）。结论利用高透氧材料的角膜塑形镜进行科学的角膜塑形治疗，对角膜代谢的影响轻微，长期配戴用于控制近视发展基本是安全的。
Objective The current study evaluated the response of the cornea to more than 3 years of Ortho-K CL wearing by investigating the changes of corneal thickness and corneal endothelium. Methods One hundred and thirty-two subjects were fitted with Ortho-K CL （ Dk 100）, which were worn overnight or daily for more than 3 years. Central and para-peripheral corneal thickness and corneal endothelium were measured before and during this period by using A scan pachymeter and non contact specular microscope. Results There were no significant changes in corneal thickness （ P 〈 0. 05 ） and corneal endothelial polymegathism and pleomorphism could not be found after long-term wearing of Ortho-K CL （ overnight or daily wear）. Conclusions This study shows that high Dk Ortho-K CL used for scientific reshaping treatment only induces mild corneal response. Therefore, the Ortho-K CL can be worn safely for long-term control of myopia.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2007年第8期680-683,共4页
Chinese Journal of Ophthalmology
关键词
近视
内皮
角膜
接触镜
Myopia
Endothelium,corneal
Contact lenses
