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血尿酸、纤维蛋白原、超敏C-反应蛋白与急性脑梗死的关系 被引量:15

Plasma Uric Acid,Fibrinogen,High Sensitive C-reactive Protein and Acute Cerebral Infarction
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摘要 目的探讨血尿酸(Uric acid,UA)、血纤维蛋白原(Fibrinogen,Fg)、超敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)在急性脑梗死中的意义。方法对脑梗死患者98例及对照组68例进行血UA、Fg、hs-CRP的检测。结果急性脑梗死患者血清UA(334.81±94.54)μmol/L、Fg(3.85±1.18)g/L、hs-CRP(5.08±5.52)mg/L水平明显增高,差异有显著性意义(P<0.05);UA与神经功能缺损程度无关,Fg、hs-CRP与神经功能缺损程度有关。结论Fg、hs-CRP与缺血性脑血管病的发生和神经功能缺损程度有关,UA与缺血性脑血管病的发生有关而与神经功能缺损程度无关。 Objective To discuss the significance of plasma uric acid(UA), fibrinogen(Fg) and high sensitive C-reactive protein(hs-CRP) in patients with cerebral infarction. Methods The plasma levels of UA, Fg and hs-CRP were measured among cerebral infarction patients( n = 98) and control group( n = 68). Results In patients with cerebral infarction, the plasma levels of UA, Fg and hs-CRP were (334. 81 ±94.54) μmol/ L, (3.85 ± 1.18) g/L and (5.08 ±5.52) mg/L, respectively, they were significantly higher than the control group( P 〈 0.05) ; the plasma Fg and hs-CRP were positively related to the neurological deficit degree in cerebral infarction patients, but there was no significant correlation between UA and neurological deficit degree. Conclusion Fg and hs-CRP were related to the formation and progression of cerebral infarction, UA was related to the formation of cerebral infarction but had no effect on the progression.
出处 《中国微循环》 北大核心 2007年第4期259-261,共3页 Journal of Chinese Microcirculation
关键词 血尿酸 纤维蛋白原 超敏C-反应蛋白 脑梗死 Uric acid(UA) Fibrinogen(Fg) High sensitive C-reactive protein(hs-CRP) Cerebral infarction(CI)
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