摘要
目的观察芪苈强心胶囊联合西药治疗中、重度慢性收缩性心力衰竭(CHF)的疗效。方法将84例CHF患者随机分为2组,对照组(42例)给予ACEI类、利尿剂、小剂量倍他乐克片(心功能IV级者心力衰竭控制后开始口服)、小剂量地高辛片等常规治疗左心衰竭;观察组(42例)在对照组治疗基础上加服芪苈强心胶囊(4粒,每日3次),2周时观察比较2组治疗效果。结果治疗2周后,观察组心功能改善总有效率、中医证候改善总有效率、左室射血分数(LVEF)提高率分别为92.9%、95.2%、(25±4)%,而对照组则分别为76.2%、81.0%、(11±3)%,2组比较差异有统计学意义(P<0.05或P<0.01)。2组均未发现明显不良反应。结论芪苈强心胶囊联合西药治疗中、重度CHF,可以更有效地改善心功能,缓解临床症状,提高左室射血分数,且安全性好。
Objective To observe the therapeutic effect of Qiliqiangxin capsule combined with western medicine on moderate and severe chronic contractive heart failure（CHF） .Methods 42 patients with CHF in control group were treated with ACEI, uretica, small dose of beta-blocker tablet （The patients with cardiac function IV grade didn＇ t take it until heart failure was controlled）, small dose of digoxin. The 42 patients in observation group, on the basis of control group, were treated by Qiliqiangxin capsule, four pills once, three times a day. The therapeutic effects were observed and compared after two-week treatment in the two groups. Results After two-week treatment, the total effective rate of cardiac function improvement, total effective rate of improvement of TCM symptoms and increasing rate of left ventricle ejection fraction （LVEF） in observation group were 92.9 %, 95.2 %, （25±4） % respectively, but which in control group were 76.2%,81.0%, （11 ± 3）% respectively. There was a significant difference between the two groups （ P 〈 0.05 or P 〈 0.01 ）. The side effects were not found in beth groups. Conclusion In the treatment of moderate and severe chronic contractive heart failure, Qiliqiangxin capsule combined with western medicine, could improve cardiac function effectively, alleviate clinical symptoms and increase LVEF, with safety.
出处
《疑难病杂志》
CAS
2007年第9期521-523,共3页
Chinese Journal of Difficult and Complicated Cases
关键词
芪苈强心胶囊
心力衰竭
收缩性
慢性
Qiliqiangxin capsule
Heart failure, contractive, chronic
