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超声及超声引导下粗针穿刺活检诊断小儿腹部神经母细胞性肿瘤的价值 被引量:4

Application of Color Doppler Ultrasound and Ultrasound-guided Core Needle Biopsy in Neuroblastoma of Children
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摘要 目的:探讨常规超声及超声引导下穿刺活检对小儿腹部神经母细胞性肿瘤的诊断价值。材料和方法:回顾性分析2000-01—2005-01的27例,小腹部神经母细胞性肿瘤(节细胞瘤5例,节细胞神经母细胞瘤7例,神经母细胞瘤15例)的常规超声表现及14例超声引导下粗针穿刺活检的病理组织学结果。结果:18例超声准确判断肿瘤神经母细胞性来源(66.7%),9例分别误诊为肾母细胞瘤(3例)、其他神经来源的肿瘤(2例)、淋巴瘤(1例)和未能提出肿瘤可疑来源的3例。本组神经母细胞性肿瘤的超声表现为较大的低回声或混合回声包块(9.25±2.96cm),形态不规则,23例可见散在的细小钙化灶,17例肿块包绕腹部大血管,节细胞瘤-节细胞神经母细胞瘤-神经母细胞瘤声像图有从均匀一致到弥漫不均的趋势;14例活检病例中,13例具体分型与术后病理相符,1例节细胞神经母细胞误诊为节细胞瘤。结论:常规超声对小腹部神经母细胞性肿瘤的诊断具有一定的帮助,而超声引导下多点的粗针穿刺活检能够明确肿瘤的分类和性质。 Purpose: Neuroblastoma was one of the most frequently encountered abdomen tumors in children. The aim of the study was to evaluate the usefulness of ultrasound (US) and US-guided core needle biopsy in pediatric abdominal neuroblastic tumors. Materials and Methods: Retrospectively from Jan 2000 to Jan 2005, were color Doppler US images of 27 neuroblastic tumors including Ganglioneuroma ( GN, n : 5 ), Ganglioneuroblastoma( GNB, n = 7 ) and Neuroblastoma ( NB, n = 15 ) analyzed along with pathologic results in 14 cases obtained via an US-guided percutaneous core needle biopsy. Results: Of 27 children, ultrasound examination accurately indicated tumor origin in 18 cases (66.7%). Nine cases was false diagnosed as Wilms'tumor ( n = 3 ), other neural origin tumors ( n = 2), lymphoma ( n : 1 ) and origin undetectable ( n = 3 ). The neuroblastic tumors appeared as large masses ( 9.25 + 2.96cm ) with big vessels encasement ( n : 17 ) and small calcifications (n = 23 ). There is a tendency of homogeneous to heterogeneous echo in order of GN-GNB-NB. In 14 biopsies, 13 had correct diagnosis and one GNB mis-diagnosed as GN in comparison to post-surgery pathology. Conclusion: US was useful in diagnosing pedi- attic abdominal neuroblastic tumors, but multi-spot US-guided core needle biopsy might be needed to provide definite tumor classification and character, ization.
出处 《中国医学影像学杂志》 CSCD 2007年第5期331-333,共3页 Chinese Journal of Medical Imaging
关键词 超声 小儿 神经母细胞性肿瘤 活检 ultrasound pediatric neuroblastic tumor biopsy
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