摘要
目的了解医院外科非发酵菌的临床分离状况及常见菌株的耐药性,指导临床合理选用抗菌药物。方法分离出的非发酵菌采用VITEK-60 AMS细菌鉴定仪鉴定,用K-B法进行体外药敏试验。结果2002年1月-2005年12月共检出非发酵菌463株,其中铜绿假单胞菌最为常见(55.07%),其次为鲍氏不动杆菌(20.52%)和嗜麦芽寡养单胞菌(11.88%);标本来源主要为痰液、引流液、伤口分泌物,分别占31.97%、13.39%、12.31%;科室来源主要是SICU、器官移植外科、烧伤外科,各占28.08%、17.28%、12.10%。居前3位的非发酵菌耐药较为严重,且呈多重耐药性。结论外科非发酵菌以呼吸道、伤口感染常见,其耐药现象严重,宜根据药敏结果选用敏感抗菌药物治疗。
OBJECTIVE To investigate the clinical distribution and drug resistance of non-fermentative bacilli isolated from department of surgery so as to guide the rational use of antibiotics. METHODS VITEK-60 AMS system and Kirby-Bauer method were used to identify the pathogenic bacilli and examine the antibiotic resistance. RESULTS A total of 463 strains of non-fermentative bacteria were isolated from Jan 2002 to Dec 2004, the most common pathogen was Pseudornonas aeruginosa （55. 07 %）, the next were Acinetobacter baumannii （20.52 %） and Stenotrophomonas maltophilia （11.88 % ）, The samples were mainly sputum（31.97 % ）, drainage （13.39 % ）, and wound secretion （12.31 %）. Isolation rate from SICU, departments of organ transplantation and burn were 28.08%, 17.28% and 12. 10%, respectively. P. aeruginosa, A. baumannii and S. maltophilia had high and multi-drug resistance. CONCLUSIONS Infections of respiratory tract and wound caused by non-fermentative bacilli are common in surgical department, and drug resistance is serious. The drugs should be chosen according to the results of the antimicrobial susceptibility tests.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第9期1147-1149,共3页
Chinese Journal of Nosocomiology
关键词
非发酵菌
临床分布
耐药性
Non-fermentative bacilli
Clinical distribution
Drug resistance
