摘要
目的探讨重型颅脑损伤患者并发抗利尿激素异常分泌综合征(SIADH)的病因、发病机制、诊断及治疗。方法回顾性分析重型颅脑损伤后发生抗利尿激素异常分泌综合征36例,通过其临床表现及实验室指标明确诊断,确定有效的治疗方法。结果7例死亡,33例低钠血症恢复。结论低血钠、高尿钠、低血浆渗透压是SIADH的特点,治疗原则以限水为主。
Objective To explore the pathogenesis,reason, diagnosis and treatment of inappropriate antidiuretic hormone secretion（SIADH） in the patients with serious cerebral injury. Methods 36 clinical cases of SIADH after serious cerebral injury were analyzed retrospectively. The diagnosis of SIADH was confirmed by clinical symp- toms of the patients and the results of laboratory examinations. Then an effective treatment was assured. Results 7 patients died and 33 patients recoverd from hyponatremia in our observed cases. Conclusion SIADH have characteristics of hyponatremia,hypernatruria and low osmitic pressure of plasma,and the major therapeutic principle is to restrict water.
出处
《中国基层医药》
CAS
2007年第9期1471-1472,共2页
Chinese Journal of Primary Medicine and Pharmacy
