摘要
目的:研究车前子多糖对便秘模型小鼠的润肠通便作用。方法:将雄性昆明小鼠随机分为空白组、模型组、阳性对照组和三个剂量的给药组。给药组分别经口给予低、中、高剂量(0.1、0.2、0.4g/kgbw)的车前子多糖;空白组和模型组给予20ml/kgbw的蒸馏水;阳性对照组给予1.0g/kgbw的麻仁丸。连续灌胃8d后,观察各组小鼠的首次排黑便时间、5h内排便粒数,测定粪便含水量和小肠墨汁推进率。结果:车前子多糖能显著缩短首次排黑便时间、增加5h内排便粒数、提高粪便含水量和小肠墨汁推进率。结论:车前子多糖具有润肠通便的作用。
Objective： To study the effect of Semen Plantaginis polysaccharidesm on defecating function in constipated mice. Methods： Male Kunming mice were randomly divided into control group, model control group, positive control group and 3 dosages groups. Mice of 3 dosages groups were administered with different concentrations of polysaccharides from Semen Plantaginis （0.1, 0.2, 0.4g/kg bw） by mouth for 8 days; mice of control group and model control group were administered with distilled water of 20 ml/kg bw for 8 days; the mice of positive control group were administered with Maren Wan of 1.0 g/kg bw for 8 days. Then the time for the first black feces to be excreted and the number mice feces within 5 hours was observed, water percent of mice feces and ink propelling rates was mensurated. Results： Semen Plantaginis Polysaccharides could markedly shorten the time for the first black feces to be excreted, Increased the number of mice feces within 5 hours. Water percent of mice feces and ink propelling rates were markedly increased too. Conclusion： Semen Plantaginis polysaccharides has the effect ofd efaecation.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2007年第10期514-516,共3页
Food Science
基金
教育部长江学者和创新团队发展计划资助项目(IRT0540)
南昌市科学技术委员会重点攻关及产业化项目(2006)
关键词
车前子多糖
通便
小鼠
便秘
Semen Plantaginis polysaccharides
defecation
mice
constipation
