摘要
目的观察颐脑解郁方对抑郁症肾虚肝郁型患者中医证候的影响。方法将60例抑郁症肾虚肝郁型患者随机分为颐脑解郁组30例和氟西汀组30例。颐脑解郁组给予颐脑解郁方治疗,氟西汀组给予氟西汀治疗,用药疗程均为6周。在治疗2周、4周、6周时,观察两组患者主要中医证候的改善情况。结果颐脑解郁方对性欲减退、时有太息的疗效在2周、4周、6周时均优于氟西汀(P<0.05或0.01);对腰酸背痛的疗效在2周、4周时优于氟西汀(P<0.01),在6周时组间比较无明显差异(P>0.05);对胁肋胀痛的疗效在2周时优于氟西汀(P<0.01),在4周、6周时组间比较无明显差异(P>0.05);对神思不聚的疗效在2周、4周时组间比较无明显差异(P>0.05),在6周时优于氟西汀(P<0.01);对忧愁善感、兴趣索然、精神委靡的疗效与氟西汀相当(P>0.05)。结论颐脑解郁方能有效改善抑郁症肾虚肝郁型患者的主要中医证候。
Objective To observe the symptomatic improvement by ＂Yinao Jieyu Prescription＂ for patients with depression of kidney deficiency and liver-qi stagnation. Methods Sixty subjects were randomly divided into two groups： Yinao Jieyu group and Fluoxetine group, 30 cases in each group. Yinao Jieyu group was treated with ＂Yinao Jieyu Prescription＂ and Fluoxetine group with Fluoxetine for six weeks. TCM symptoms were observed on 2nd, 4th and 6th weeks of treatment. Results Curative effects of ＂Yinao Jieyu Prescription＂ on deficiency of sexuality and frequent sigh were better than those of Fluoxetine on the 2nd, 4th and 6th week, P〈 0.05 or 0.01; curative effects on pain in the waist and back were better than those of Fluoxetine on the 2nd and 4th weeks, P〈 0.01, and had no significant difference between the two groups on the 6th week, P〉 0.05; curative effect on swelling and pain in the flank was better than that of Fluoxetine on the 2nd week, P〈0.01, and had no significant difference between the two groups on the 4th and 6th weeks, P〉0.05; curative effect on inattention had no significant difference between the two groups on the 2nd and 4th weeks, P〉 0.05, and was better than that of Fluoxetine on the 6th week, P〈0.01; curative effect on melancholy, boredom and listlessness had no significant difference between the two groups, P〉0.05. Conclusion ＂Yinao Jieyu Prescription＂ is effective in improving symptoms in patients with depression of kidney deficiency and liver-qi stagnation.
出处
《上海中医药杂志》
北大核心
2007年第10期26-28,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
首都医学发展科研基金(中医药)联合攻关项目课题(03-Ⅰ-02)
关键词
抑郁症
肾虚肝郁
颐脑解郁方
氟西汀
中医证候
Depression
kidney deficiency and liver-qi stagnation
＂Yinao Jieyu Prescription＂
Fluoxetine
TCM syndrome
