摘要
目的采用紫外分光光度法测定红霉素明胶微球的含量。方法紫外分光光度法。结果红霉素溶液在0．0191～0．0522mg·mL^-1浓度范围内，吸收度与浓度之间呈良好的线性关系C=0．0663A-0．0008mg·mL^-1，r=0．9999：总平均回收率99．91％，RSD=0．28％（r=9）。结论该方法操作简便，结果准确可靠，适用于该制剂的质量评价。
OBJECTIVE To determine erythromycin content in erythromycin gelatin microspheres. METHODS Erythromycin was determined at 482 nm and blank control had little interference. Methods ： Ultraviolet spectrophotometry was used. RESULTS The erythromycin presented linear within the range of 0. 0191 -0. 0522mg ·mL^-1 ,r =0. 9999. The recovery was 99.91% ,RSD =0. 28% （n =9）. CONCLUSION This method is simple,rapid,and accurate in content determination of erythromycin gelatin microspheres.
出处
《海峡药学》
2007年第10期65-66,共2页
Strait Pharmaceutical Journal
基金
广东省科技计划资助项目(2005B30101015)
广州市科技计划资助项目(2005z3-E0541)
关键词
紫外分光光度法
红霉素明胶微球
含量测定
UV Spectrophotometry
Erythromycin gelatin microspheres
Determination
