摘要
用电感耦合等离子体质谱法（ICP—MS），建立了不同化妆品基质中铬的测定分析方法。样品预处理采用以HNO3水溶液作消化试剂的微波消解方法，并对5种不同化妆品基质中消化试剂的用量进行了比较。优化选择电感耦合等离子体质谱仪的工作参数，考察了测量过程中的基体效应及质谱干扰，针对不同化妆品样品，选择^52Cr、^53Cr作为测量同位素，^72Ge为内标元素，对试样进行定量分析，有效地补偿基体效应所引起的测量偏差。实验证明，^52Cr、^53Cr的检测结果差异不大，均能满足化妆品中铬的测定要求。对照分析了参考标准物质。铬质量浓度在0．1～100μg/L范围内，校正曲线的相关系数为0．9999；铬添加质量浓度为0．5mg／kg，添加平均回收率为85．3％～104％；相对标准偏差（RSD）为1．5％～7．3％，^52Cr检出限为0．052μg/kg，^53Cr检出限为0．036μg/kg。
A method was established for the determination of trace Cr in different cosmetic substrates by inductively coupled plasma-mass spectroscopy（ICP-MS）. The sample was prepared by microwave digesting in HNO3-H2O2. Comparison research on the dosage of digesting reagent for five different cosmetic substrates was carried out. The working parameters of ICP-MS were optimized, and the matrix effect and the mass interferences were inspected; ^52Cr and ^53Cr were selected as the target isotopes, ^72Ge as the internal standard element, and the influence due to matrix effect were compensated effectively. The experiments showed that the analysis results based on ^52Cr and ^53Cr was not obvious different, which satisfies the determination of Cr in cosmetics. Standard reference samples were analyzed, with the Cr concentration range of 0. 1 - 100 μg/L. The correlation coefficient was 0. 999 9, and with 0. 5 mg/kg Cr doped, the average rate of recovery was around 85.3% - 104%. The relative standard deviations（RSD） were 1.5% - 7.3%, the detection limit of ^52Cr 0. 052μg/kg, and the detection limit of ^53Cr 0. 036 μg/kg.
出处
《应用化学》
CAS
CSCD
北大核心
2007年第11期1340-1342,共3页
Chinese Journal of Applied Chemistry
