摘要
目的了解北京市流行性感冒(流感)流行规律和毒株的变异动态,为及早发现和控制疫情提供科学依据。方法2001～2005年以人民医院和市儿童医院作为哨点医院,对流感的流行病学、病原学、血清学监测结果进行分析。结果连续4年在1979780例门诊病例中监测到流感样病例197707例;检测流感样病例咽拭子标本1778份,分离出流感病毒444株,其中甲1亚型29株(6.53%),甲3亚型331株(74.55%),乙型84株(18.92%);9、4月份分别采集普通人群血清标本158件和300件,流感病毒各型抗体中H3N2亚型抗体阳性率最高,流行高峰前、后分别为98.10%和98.33%,其它两个型别阳性率也较高。结论2001～2005年北京市流感的流行情况较为平静;H3N2为4年流感流行的优势株,今后须密切关注甲型的抗原变化和加强流感的监测工作。
Objective To understand the pattern of influenza incidence and influenza viral variation in Beijing to provide scientific basis for early detection and control of its epidemic. Methods Data of influenza epidemiology, pathogen and serology in sentinel surveillance from the People＇ s Hospital of Peking University and Beijing Children＇ s Hospital during 2001 to 2005 were used for analysis. Results Totally, 197 707 cases of influenza like illnesses （ILI） were collected from 1 979 780 outpatient visits during 2001 to 2005, and 444 strains of influenza virus were isolated from 1 778 specimens of ILI cases and 6.53% （29 strains） were identified as type A/H1N1, 74.55% （331） as A/H3N2 and 18.92% （84） as type B. Serum positive rate of antibody against H3N2 was 98.10% in general population in Septembers and 98.33% in Aprils, and serum positive rate of antibody against A/H1N1 and type B was all more than 50% . Conclusion Influenza was not prevalent in Beijing during 2001 to 2005, with A/H3N2 as predominant strain. It is important to pay more attention to variation of its hemagglutinin antigen and to strengthen its surveillance,
出处
《首都公共卫生》
2007年第5期197-199,共3页
Capital Journal of Public Health
关键词
流行性感冒
流感病毒
监测
Influenza
Influenza virus
Surveillance
Monitoring
