摘要
慢性肾脏病是值得关注的公共卫生问题。实验室技术人员和临床医生认识到估算肾小球滤过率(eGFR)在慢性肾脏病筛查中应该注意的若干问题和各种人血清肌酐测定系统的分析性能对其估算值的影响,对于肾脏病膳食改善(Modification of Diet in Renal Disease,MDRD)方程在慢性肾脏病(CKD)诊断、治疗中的正确应用具有作用。本文介绍了各种常用肌酐测定系统间的变异、偏倚对 eGFR 估算值的影响及国际人血清肌酐测定标准化的进展。
Chronic kidney disease （CKD） is a major public health problem worldwide. Understanding by doctors and laboratorians of the importance of reliable serum creatinine measurement in GFR estimation and of factors that may affect creatinine measurement is critical to ongoing public health efforts to improve the diagnosis and treatment of patients with CKD. We present an overview of the commonly used methods, their performances and limitations and the required performance criteria for the measurement of serum creatinine. Available resources for standardization of serum creatinine measurements and recommendations for creatinine measurement and GFR estimations are introduced.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2007年第11期1207-1210,共4页
Chinese Journal of Laboratory Medicine
关键词
肌酐
肾小球滤过率
标准化
Creatinine
Glomerular filtration rate
