摘要
为了解小儿与成人肾病综合征（NS）病理及临床疗效差异。对同期住院的小儿与成人把各350例的临床分型、病理类型及疗效进行比较。结果小儿组中，单纯性肾病占77．1％（270例），肾炎性肾病占22．9％（80例）；成人组中，NSI占44．9％（157例）、NSII占55．1％（193例）。病理类型：MCD、MsPGN、IgAN、EnP小儿多于成人，MN、FsGS、MPGN、CrGN成人较小儿多见，PSGN、SGN仅见于成人。小儿组完全缓解82．6％，成人组完全缓解67.1％。结论：小儿组以单纯性肾病最多见，成人组以NSⅡ多见，小儿组病理改变数成人组轻，疗效小儿组明显优于成人组。
To investigate the difference of pathology and clinical therapeutic effects between children and adults suffering from nephrotic syndrome (NS),a comprehensive study was carried out about the pathologic types and the therapeutic effects among 700 cases of children and adults simultaneously hospitalized because of NS. out of 350 cases of children, 270(77. 1%) suffered from simple NS and 80 (22. 9%) from nephritic NS,while for the adults 157(44- 9%) out of 350 cases were affected with NS I and 193(55. 1 % )with NSⅡ. As far as the pathologic typpes are concerned,MCD, MsPGN,IgAN and EnP were seen more in children than in adults while MN, FsGN, MPGN and CrGN were observed more in adults. Serious pathologic change, PSGN or SGN,was found only in adults of NS. Therapeutic effects show that the complete remission rate for children is 82. 6% while that for adults was 67. 1% (P<0. 01). It is concluded that simple nephropathy is more affected by children and NS Ⅱ is the majer condition for adults. and children's pathologic changes are not so great as those for adults And thus their curative effects are more favorable.
关键词
肾病综合征
病理
小儿
成人
疗效
药物疗法
Nephrotic syndrome Clinicopathology and therapeutic Effect comparison Children and adults
