摘要
目的了解儿童接种甲肝疫苗后人群甲肝总抗体水平。方法按不同年龄分成2组,于1996年疫苗接种前及2005年儿童接种疫苗后9年,分别抽取正常人群720名和803名,用ELISA法检测血清甲肝总抗体。结果青少年及儿童(18岁以下)抗体阳性率由接种前的29.84%提高到接种后的64.15%(P<0.01)。成人组(25～35)抗体阳性率从78.92%到84.47%,差异无统计学意义(P>0.05)。结论儿童接种甲肝疫苗提高了抗体水平,没有发现疫苗接种后易感人群后移。
Objective To understaid the effect on HAV antibody levels of population after children vaccinated against viral hepatitis A. Methed Two groups of children from Weifang City of Shandong Province were divided into seven subgroups according to ages respectively. 720 subjects（group 1）were detected of anti-HAV-IgG levels in 1996, and 803 ones （group 2） were detected in 2005 after nine years of mass vaccination.ELISA method was used in serum test.Result Anti-HAV-IgG rate of whole population increased significantly.The positive rate in adolescents and children （〈18 years old） increased from 29.84% to 64.15% （P〈0.01）,and in adults （25 to 35 years old） from 78.92% to 84.47% with no statistical significance （P〉0.05）.Conclusion HAV antibody levels of population in children significantly increase after vaccinating against viral hepatitis A, and no retrocession in age groups of susceptibility is found.
出处
《预防医学情报杂志》
CAS
2007年第3期272-273,共2页
Journal of Preventive Medicine Information
关键词
甲型肝炎
减毒活疫苗
抗体
Hepatitis A
Live attenuated vaccine
Anti-HAV-IgG
