摘要
自1994年3月至1995年12月,应用顺铂和白细胞介素-2联合腔内灌注,治疗癌性积液52例,结果:完全缓解32例(61.5%),部分缓解16例(30.8%),总有效率92.3%。对癌性胸腔和腹腔积液的有效率分别为92.3%和91.7%,2例癌性心包税液均有效。毒副作用轻微,仅少部分病人有轻度的恶心、呕吐和低热,未发现有骨髓抑制和心、肝、肺和贤肾等功能损害。
From Mareh 1994 to December l995, fifty - two Patients with cancerous effosions were ed with combined intracavitary infusion of cisplatin and interleukin-2.In this series,32cases (61.5%)achieved complete relnission, l6 cases (30.8% ) Partial rendssion, the total effective rate was 92.3%.The effective rates for anrous Pleural peritotal dsions were 92.3% and 9l .7% respectively. Both of the two Patients with cancemes periedal effesion echieved rendssion. The toxicities were well tolerated A few of thee mpents experienced mild nausea, vomiting and fever. No myelosupperssion and damages of the functions of the heart, the kidenies and the lungs were found.
出处
《河南肿瘤学杂志》
1997年第3期200-202,共3页
Henan Journal of Oncology
关键词
癌性积液
腔内联合灌注
顺铂
IL-2
cancerous effusion,intracavitary combination infusion,cisplatin and interleukin-2