期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

多发性骨髓瘤血栓形成及防治的研究进展 被引量：3

原文传递
导出
摘要 多发性骨髓瘤（MM）是一种浆细胞异常增生的恶性肿瘤，其发生血栓事件的危险度很高，尤其是静脉血栓栓塞。MM导致血栓事件发生的原因很多，包括恶性肿瘤本身易并发血栓、MM患者血液的高凝状态以及免疫调节剂的应用。MM患者常应用化疗药物或者类固醇药物联合免疫调节剂如沙利度胺或其类似物雷利度胺的治疗方案，使静脉血栓栓塞的发生率增加。目前临床上常应用低分子量肝素钠、华法林及阿司匹林来预防血栓的形成，并且取得了较好的效果。
作者 刘增艳（综述） 陆化（审校）
机构地区 南京医科大学第一附属医院血液科
出处 《国际输血及血液学杂志》 CAS 2007年第6期499-501,共3页 International Journal of Blood Transfusion and Hematology
关键词 多发性骨髓瘤 血栓形成 免疫调节剂
分类号 R733.3 [医药卫生—肿瘤]
  • 相关文献

参考文献20

  • 1Wojtukiewicz MZ, Sierko E, Klement P. et al. The hemostatic system and angiogenesis in malignancy. Neoplasia, 2001,3 ( 5 ) : 371-384.
  • 2Sallah S. Husain A, Wan J, et al. The risk of venous thromboembolic disease in patients with monoclonal gammopathy of undetermined significance. Ann Oncol,2004,15(10): 1490- 1494.
  • 3Srkalovic G, Cameron MG, Rybicki L, et al. Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic diseasc. Cancer, 2004,101 (3) : 558-566.
  • 4Rajkumar SV, Blood E, Vesole D, et al. Phase Ⅲ clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol.2006.24(3) :431-436.
  • 5Barlogie B, Desikan R, Eddlemon P, et al. Extended survival in advanced and refractory multiple myeloma after single agent thalidomide : identification of prognostic factors in a phase 2 study of 169 patients. Blood,2001,98(2):492-494.
  • 6Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med, 1999, 341(21):1565-1571.
  • 7Baz R, Li L, Kottke-Marchant K, et al. The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline based chemotherapy for multiple myeloma. Mayo Clin Proc, 2005,80(12) : 1568-1574.
  • 8Palumbo A, Rus C, Zeldis JB, et al. Enoxaparin or aspirin for the prevention of recurrent thromboembolism in newly diagnosed myeloma patients treated with melphalan and prednisone plus thalidomide or lenalidomide. J Thromb Heamost,2006,4(8) : 1842- 1845.
  • 9Rajkumar SV, Blood E. Lenalidomide and Venous Thrombosis in MultipleMyeloma. N Engl JMed,2006,354(19):2079-2080.
  • 10Zangari M, Elice F, Fink L, et al. Thrombosis in multiple myeloma. Anticancer Ther,2007,7(3) : 307-315.

同被引文献33

  • 1李大鹏,李振,侯兆红,徐学芳,任红.骨科围手术期凝血功能等指标的监测及其临床意义[J].临床军医杂志,2005,33(1):21-23. 被引量：4
  • 2YING Ke-jing,ZHOU Yong,JIANG Hao,CHEN En-guo,ZHOU Pan.Multiple myeloma with pulmonary embolism:a case report[J].Chinese Medical Journal,2006(17):1481-1484. 被引量：1
  • 3陈杰,陶惠民,童培建,杨迪生.多发性骨髓瘤的外科治疗[J].实用肿瘤杂志,2007,22(1):40-44. 被引量：9
  • 4王鸿利.多发性骨髓瘤实验诊断的进展[J].临床内科杂志,2007,24(9):581-583. 被引量：10
  • 5陆再英,钟南山,主编.内科学[M].第7版.北京:人民卫生出版社,2008:778-779.
  • 6Martini WZ, Cortez DS, Dubick MA, et al. Thrombelastography is better than PT, aPTT, and activated clotting time in detecting clinically relevant clotting abnormalities after hypothermia, hemorrhagic shock and resuscitation in pigs. J Trauma, 2008, 65(3):535-543.
  • 7Lee TH, McCully BH, Underwood S J, et al. Correlation of conventional thrombelastography and rapid thrombelastography in trauma. Am J Surg, 2013, 205(5):521-527.
  • 8Ustuner Z, Akay OM, Keskin M, et al. Evaluating coagulation disorders in the use of bevacizumab for metastatic colorectal cancer by thrombelastography. Med Oncol, 2012, 29(5): 3125-3128.
  • 9Meier J. A new application for thrombelastography in pregnant women at term. Minerva Anestesiol, 2012, 78(12): 1319-1320.
  • 10Weng WW, Dong M J, Zhang J, et al. A systematic review of MRI, scintigraphy, FDG-PET and PET/CT for diagnosis of multiple myeloma related bone disease--which is best? Asian Pac J Cancer Prev, 2014, 15(22):9879-9884.

引证文献3

二级引证文献11

国际输血及血液学杂志
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部