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癌症患者化疗前后疲劳状况及其影响因素 被引量:16

Survey fatigue in cancer patients before and after chemotherapy
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摘要 目的:调查肿瘤患者化疗前后疲劳状况并探讨其影响因素。方法:应用翻译的FSI量表及自行编制的疾病及一般情况登记表,对121例住院肿瘤患者进行面对面问卷式调查,计算FSI量表各维度得分,采用方差分析方法分析其主要影响因素。结果:肿瘤病人化疗前不同性别、不同肿瘤分期疲劳评分有明显差异(P<0.05)。化疗后疲劳评分多有不同程度的增加,差异有统计学意义(P<0.01)。使用不同化疗方案的患者化疗后疲劳评分有显著差异(P<0.05)。化疗过程中有恶心呕吐症状者化疗后疲劳各维度评分均明显增高(P<0.05)。结论:肿瘤病人化疗后疲劳评分明显增高。女性、肿瘤分期晚、联合化疗、化疗中有恶心呕吐症状疲劳评分较高,不同的化疗药物所导致的疲劳程度不同。 Objective:To investigate the status of fatigue in cancer patients before and after chemotherapy and its affecting factors.Methods:To measure fatigue in 121 cancer patients receiving chemotherapy,Fatigue Symptom Inventory and self-administered questionnaire and personal interview methods were used.Data analysis was performed by SPSS software,including analysis of variance and T test.Results:The FSI scores increased significantly after chemotherapy.Its intensity was 2.55±1.43/3.98±1.75,the duration was 4.14±2.45/5.71±2.16,and the influence of quality of life was 1.52±0.81/2.11±1.13.Gender and cancer stage were significantly related with fatigue of cancer patients before chemotherapy.After chemotherapy,the fatigue was associated with nausea and vomiting during chemotherapy and the manner in which cytotoxic agents were administered.Conclusion:The FSI score significantly increased after chemotherapy.The fatigue was severe in women,late stage,combined chemotherapy,nausea and vomiting and chemotherapy drugs contained platiniferous ones.
出处 《现代肿瘤医学》 CAS 2007年第10期1496-1498,共3页 Journal of Modern Oncology
关键词 肿瘤 化疗 疲劳 cancer chemotherapy fatigue
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参考文献8

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二级参考文献7

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