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腹腔镜与开腹卵巢子宫内膜异位囊肿剔除术对机体微炎症和氧化应激影响的比较 被引量:9

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摘要 目的:比较腹腔镜与开腹卵巢子宫内膜异位囊肿剔除术对机体微炎症和氧化应激的影响。方法:将50例卵巢子宫内膜异位囊肿患者分为腹腔镜囊肿剔除术25例(腹腔镜组)和开腹囊肿剔除术25例(开腹组)。所有患者均分别于手术前、术后1d和术后3d时取静脉血,散射比浊法测定血清C反应蛋白(CRP),ELISA双抗体夹心法测定血清IL-6和肿瘤坏死因子(TNF-α),硫代巴比妥酸比色法测定血浆丙二醛(MDA),羟胺法测定血浆超氧化物歧化酶(SOD)。结果:两组术后1d时CRP、IL-6、TNF-α水平均明显高于术前,术后3d时开腹组CRP进一步升高,其余指标有所回落,开腹组术后1、3d时CRP、IL-6、TNF-α水平均明显高于腹腔镜组。腹腔镜组术后1、3d时MDA、SOD水平与术前比较差异无显著性;开腹组术后1d时MDA明显升高,而SOD明显降低,术后3d时均有所恢复,但未恢复至术前水平;术后1、3d时开腹组MDA均高于腹腔镜组,而SOD均低于腹腔镜组。结论:腹腔镜卵巢子宫内膜异位囊肿剔除术手术创伤小,术后微炎症反应轻,机体氧化应激反应较剖腹手术低,且恢复迅速。
出处 《实用医学杂志》 CAS 2007年第22期3536-3537,共2页 The Journal of Practical Medicine
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