摘要
目的:采用G6PD/6PGD比值法,对昆明地区705名男性新生儿及728名女性新生儿进行葡萄糖-6-磷酸脱氢酶缺乏症筛查。结果:男性新生儿葡萄糖-6-磷酸脱氢酶缺乏症发生率为5.11%,女性新生儿发生率为7.55%。昆明作为此症的高发地区,常规开展新生儿葡萄糖-6-磷酸脱氢酶缺乏症筛查工作可使临床医生对缺乏症患者及时采取综合性预防措施,避免因出现核黄疸而致的智力低下或死亡等后果,从而提高优生优育水平。结论:G6PD/6PGD比值法能较为有效地检出女性杂合子,具有明显的优点。
Objective： G6PD/6PGD ratio quantitative NBT method was used to screen 705 male newborns and 728 female newboms in Kunming area. Results： The newborn ratio of glucose - 6 - phosphate dehydrogenase （ G - 6 - P） deficiency was 5.11% in reals and 7. 55% in females. It was necessary to perform newborn screening of G -6 -P deficiency routinely in Kunming because of its high disease prevalence. The clinicians can give treatments on newborns with G- 6 -P deficiency to prevent kernicterus and death. Conclusion： G6PD/ 6PGD ratio quantitative NBT method is an effective method to detect heterozygous female newborns.
出处
《中国妇幼保健》
CAS
北大核心
2007年第36期5190-5191,共2页
Maternal and Child Health Care of China
