摘要
目的探讨孤立性纤维性肿瘤(solitary fibrous tumor,SFT)的影像学表现及其病理学特征,进一步提高对该病的认识与诊断水平。方法回顾性分析8例孤立性纤维性肿瘤的SFT影像学表现,并与病理组织学及免疫组化对照观察。结果(1)孤立性肿块边缘光滑清晰,位于肺部2例,盆腔2例,颈部2例,腹膜后1例,上颌窦1例。(2)CT检查孤立性肿块部分可见囊性退变区,增强扫描肿瘤实质部分明显强化。(3)MRI检查肿瘤实质在T1WI及T2WI上呈低信号,较大的肿瘤在T2WI上呈高低混杂信号且可见血管流空信号。(4)病理学检查肿瘤由梭形细胞构成,血管丰富,管腔呈裂隙样改变,免疫组化CD34、CD99阳性。结论SFT是一种间叶源性软组织肿瘤,可发生在全身各部位。影像学上见孤立性、境界清楚的软组织肿块,肿块血管丰富、明显强化,尤其当肿块实质部分在T1WI呈中等或低信号而T2WI上以低信号为主时应考虑到该肿瘤,确诊需靠病理学及免疫组化检查。
Objective To study the pathological and imaging features of the solitary fibrous tumors（SFT）and improve the diagnosis of the SFT . Methods 8 patients with SFT who were confirmed by reviewing patients surgical and pathology records were retrospectively analyzed and a comparison with histopathological and immunohistochemical results was made. Results （1） A smooth margined solitary mass was founded in the lung in two cases, in the cavity of pelvis in two cases,in the cervical part in two cases,in the retroperitoneal phyma and in the maxillary sinus in one case. （2）On CT scans, cystic degeneration area and marked enhancement of tumor＇s parenchyma were demonstrated. （3） On T2WI, most tumors were hypointense, and larger lesions displayed low-high mixed signal with signal void of flow. （4）Microscopically,SFTwas composed of spindle cells arranged in different patterns,with CD 34 ,CD99 being immunohistochemical positive. Conclusion SFT is a soft tissue tumor originated from mesenchyma. The possibility of SFT should be considered when a soft tissue mass with sharp border,marked enhancement of tumor＇s parenchyma and on T1WI intermediate or hypointensed while on T2WI hypointensed tumor is seen on imaging examination. However, the verification of the diagnosis should he based on the histopathological and immunohistochemical examinations.
出处
《江西医学院学报》
CAS
2007年第6期63-65,F0003,共4页
Acta Academiae Medicinae Jiangxi
关键词
孤立性纤维性肿瘤
影像诊断
病理学
免疫组织化学
solitary fibrous tumor
diagnostic imaging
tomography
pathology immunohistochemistry
