摘要
目的研究市场上化妆品中抗生素、防腐剂的含量情况。方法在广州市化妆品市场分别选择专业批发市场和零售市场(商场、超市)的化妆品,利用高效液相色谱法进行4种抗生素(土霉素、四环素、金霉素、氯霉素)和5种防腐剂(对羟基苯甲酸、对羟基苯甲酸甲酯、对羟基苯甲酸乙酯、对羟基苯甲酸丙酯、对羟基苯甲酸丁酯)的检测。结果共检测111件样品,30件检出土霉素,62件检出四环素,7件检出金霉素,1件检出氯霉素,阳性检出率是78.4/,不同类别化妆品抗生素的检出率差异无统计学意义;多数化妆品添加对羟基混合酯类的防腐剂,有4件样品防腐剂超标。结论市售化妆品中添加抗生素情况较严重。卫生部门应尽快制定抗生素和防腐剂的检测标准和检测方法,开展化妆品中抗生素和防腐剂的检测和卫生监督。
Objective To study the contents of antibiotics and antiseptics in the cosmetics sold in markets. Methods The cosmetics sold in professional market and current market （in which cosmetics were retailed） were selected respectively in Guangzhou and the contents of four antibiotics （oxytetraeycline, tetracycline, chlortetracycline and chloramphenicol） and five antiseptics （para-hydroxybenzcic acid, methyl para-hydroxybenzoate, ethyl para-hydroxybenzoate, propyl para-hydroxybenzoate and butyl para-hydroxybenzoate） were determined by high performance liquid chromatogram. Results In 111 cosmetics, 30 cosmetics were detected containing oxytetracycline, 62 cosmetics containing tetracycline, 7 cosmetics containing chlortetracycline and 1 cosmetic containing chloramphenicol. The detection rate was 78.4% and the detection rate of antibiotics among various kinds of cosmetics had no significant difference. The antiseptics used in cosmetics were mostly para-hydroxyl compound ester and there were four cosmetics detected containing antiseptics. Conclusion Abusing antibiotics in cosmetics market is very serious. The test standards and methods for antibiotics and antiseptics in the cosmetics should be developed as soon as possible. Cosmetic enterprises need to decrease microbe pollution in the process of production and prohibit adding antibiotics in cosmetics.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2007年第6期440-442,共3页
Journal of Environment and Health
基金
广州市医药卫生科技项目(2005-YB-121)
关键词
化妆品
抗生素
防腐剂
Cosmetic
Antibiotic
Antiseptic
