摘要
目的观察联合生长抑素和硫酸镁治疗重症急性胰腺炎(SAP)的疗效。方法56例SAP患者随机分为联合生长抑素与口服硫酸镁治疗组(n=29)和生长抑素组(n=27),比较两组间入院时与治疗3 d及5 d后血、尿淀粉酶及白细胞水平的差值的差异,比较两组腹痛、腹胀、发热、禁食、住院的时长及并发症发生率差异。结果联合治疗组治疗3 d和5 d后,血、尿淀粉酶及白细胞水平的下降幅度均高于生长抑素组(P<0.05)。联合治疗组腹痛、腹胀、发热、禁食、住院的时长和并发症发生率均小于生长抑素组(P<0.05)。结论联合生长抑素和口服硫酸镁治疗SAP是一种疗效可靠、简便易行的方法,值得推广。
Objective To study the effects of combined use of sandostatin and magnesium sulfate in the treatment of severe acute pancreatitis. Methods 56 cases were randomly divided into combined treatment group in which used magnesium sulfate and somatostatin （n =29） and so- matostatin group（n =27）. The changes of urinary amylase, blood amylase, white blood cells from the hospital admission to the third day or the fifth day were observed. The length of stomachache, abdominal distension, fever, fasting, or stay in hospital and complications were recorded. Results The decrease of urinary amylase, blood amylase or white blood cells from the hospital admission to the third day or the fifth day in combined therapy group was higher than that in group of somatostatin, respectively （P 〈0.05, respectively）. The length of stomachache, abdominal distension, fever, fasting, stay in hospital or incidence rate of complications in combined treatment group was lower than that in group of somatostatin, respectively （P 〈 0.05, respectively）. Conclusion The combined use of magnesium sulfate and somatostatin is an effective and feasible method to treat severe acute pancreatitis combined.
出处
《湖北民族学院学报（医学版）》
2007年第4期33-35,共3页
Journal of Hubei Minzu University(Medical Edition)
关键词
硫酸镁
生长抑素
重症急性胰腺炎
Magnesium sulfate
Somatostatin
Severe acute pancreatitis
