期刊文献+

热休克蛋白对细胞凋亡的调控及其应用 被引量:1

Regulation of heat shock proteins on apoptosis and its application
原文传递
导出
摘要 热休克货白(HSP)对细胞凋亡有双向调控作用,尤其是其抗细胞凋亡的作用为临床多种疾病的治疗开辟了新的途径。 Heat shock protein(HSP) shows both biological effects of up-regulation and down-regulation on apoptosis. Especially the suppressive effects on apoptosis provide a new path to treat various diseases.
出处 《国际肿瘤学杂志》 CAS 2007年第12期881-883,共3页 Journal of International Oncology
基金 上海市科委自然科学基金资助项目(05zr14120)
关键词 热休克蛋白质类 细胞凋亡 线粒体 Heat shock proteins Apoptosis Mitochondria
  • 相关文献

参考文献18

  • 1Parcellier A,Gurbuxani S,Schmitt E,et al.Heat shock proteins,cellular chaperones that modulate mitochondrial cell death pathways.Biochem Biophys Res Commun,2003,304(3):505-512.
  • 2Gupta S,Knowhon AA.HSP60,Bax,apoptosis and the heart.J Cell Mol Med,2005,9(1):51-58.
  • 3Garrido C,Brunet M,Didelot C,et al.Heat shock pmteins 27 and 70:anti-apoptotic proteins with tumorigenic properties.Cell Cycle,2006,5(22):2592-2601.
  • 4Aghdassi A,Phillips P,Dudeja D,et al.Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.Cancer Res,2007,67(2):616-625.
  • 5Zong WX,Li C,Hatzivassiliou G,et al.Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.J Cell Biol,2003,162(1):59-69.
  • 6Hitomi J,Katayama T,Taniguchi M,et al.Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.Neurosci Lett,2004,357(2):127-130.
  • 7Clemons NJ,Buzzard K,Steel R,et al.Hsp72 inhibits apoptosis upstream of the mitochondria in type Ⅱ cells.J Biol Chem,2005,280(10):9005-9012.
  • 8Gabai VL,Mabuchi K,Mosser DD,et al.Hsp72 and stress kinase ejun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis.Mol Cell Biol,2002,22(10):3415-3424.
  • 9Gotoh T,Terada K,Oyadomari S,et al.hsp70-DnaJ chaperone pair prevents nitric oxide-and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.Cell Death Differ,2004,11(4):390-402.
  • 10Gurbuxani S,Schmitt E,Cande C,et al.Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.Oncogene,2003,22(43):6669-6678.

同被引文献8

引证文献1

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部