摘要
目的:观察金乌骨通胶囊治疗寒湿痹阻型强直性脊柱炎(AS)的临床疗效及不良反应。方法:将60例患者随机分为2组,治疗组予金乌骨通胶囊,对照组予柳氮磺吡啶(SASP),比较两组患者治疗后各项疗效评价指标的改善情况并记录不良反应。结果:治疗组有效率为86.67%,对照组有效率为83.33%,两组间疗效比较差异无统计学意义,P>0.05。金乌骨通胶囊组治疗后的晨僵时间、Schober试验、指地距、疼痛、ESR、CRP等临床及实验室指标,与治疗前比较差异有统计学意义,P<0.05。治疗后晨僵时间、Schober试验、指地距、疼痛等指标与对照组比较,差异有统计学意义,P<0.05。金乌骨通胶囊组不良反应明显少于对照组。结论:金乌骨通胶囊治疗寒湿痹阻型AS疗效肯定,无明显不良反应,适合该型患者临床使用。
Objective： To evaluate clinical curative effects and adverse effects of jinwugutongjiaonang treating AS patients who were the type of cold wetness blocked in Joints. Methods： Sixty patients were randomly diuided into to 2 groups. The treatment group was treated with jinwugutongjiaonang and the control group was treated with SASP, We observed the signs and symptoms, chemical examination result and record adverse effect after treatment of 2 groups, Result： The effective rate of the treatment group was 86. 67% and that of the control group was 83.33%,which had no significant differences in 2 groups （P〉0.05）. Morning stiffness time, Schober test, finger-ground test, pain score, ESR and CRP had significant differences before and after treatment of jinwugutongjiaonang group, P〈0. 05, Morning stiffness time, Schober test, finger--ground test and pain score had significant differences between 2 groups after treatment, P〈0.05. Adverse effect of jinwugutongjiaonang was less than that of SASP, Conclusion： It had been proved to be effective and safe to apply jinwugutongjiaonang which suited to AS patients who were the type of cold wetness blocked in Joints.
出处
《中国中医骨伤科杂志》
CAS
2008年第1期28-29,共2页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
金乌骨通胶囊
强直性脊往炎
柳氮磺吡啶
Jinwugutongjiaonang
Ankylosing spondylitis
Salicylazosulfapyridine
