摘要
目的观察阿卡波糖治疗老年冠心病合并糖耐量减低的疗效。方法35例患者均口服阿卡波糖50mg,3次/d,随访13周。结果治疗后4周患者餐后2h血糖明显下降(P<0.01),治疗后13周患者颈动脉内中膜厚度明显降低(P<0.05),治疗后除甘油三酯降低外,肝、肾功能无明显变化。结论阿卡波糖能有效降低冠心病合并糖耐量减低患者餐后血糖,延缓动脉粥样硬化的发展。
Objective To investigate the efficacy of acarbose on coronary heart disease complicated with impaired glucose tolerance （IGT）. Methods The administration was acarbose 50 mg, 3 times daily, for 35 cases of coronary heart disease complicated with IGT, The patients were followed for 13 weeks, Results Plasma glucose of steamed bread meal 2 h （2 h PG） was lowered obviously after 4 weeks of treating （P〈0.01）; intimamedia thickness （IMT） of carotid arteries was thin obviously after 13 weeks of treating （P〈0.05）;no obvious changes of renal and liver function existed except triglyceride reduced, Conclusion Acarbose is effective in reducing 2 h PG and slowing down the progress of arteriosclerosis.
出处
《中国药业》
CAS
2008年第3期40-41,共2页
China Pharmaceuticals
关键词
冠心病
糖耐量减低
阿卡波糖
coronary heart disease
impaired glucose tolerance
acarbose
