摘要
目的:通过对共同性斜视患者眼外肌的病理学研究,了解其发病机制及手术时机。方法:用光学显微镜和电子显微镜对56例共同性斜视的眼外肌进行观察。结果:斜视患者弱侧眼肌不同程度萎缩变性,肌原纤维稀疏,H带不清,肌原纤维排列方向紊乱,线粒体多,嵴密,肌质网扩张,有些有髓神经髓鞘层次不清,轴突水肿,随病程延长,肌纤维病变加剧。结论:共同性斜视患者斜视弱侧眼肌在结构上有明显的病理性改变,萎缩变性是产生共同性斜视的重要原因。斜视患者应尽早行手术治疗。
AIM： To investigate the mechanism and the best operation time for concomitant strabismus by studying the pathological changes of extraocular muscles. METHODS： The pathological ultrastructure of extra-ocular muscles was observed with light and electron microscope in 56 specimens of concomitant strabismus. RESULTS： The muscle fibers of weaker ocular muscle atrophied or degenerated to different extent and myofibrils became thinly scattered. H band was not clear. Arrangement direction of myofibrils were in disorder. There were many mitochondria and mitochondrion crista became thick. Sarcoplasmic reticulum was enlarged. Levels of myelin sheath were confused in some medullated nerves. Axons became edematous. The pathological change of myofibers became more obvious with the prolongation of the course. Parts of stronger ocular muscle had slight degeneration. CONCLUSION： Remarkable pathological changes of structure existed in weaker ocular muscles of concomitant strabismus patients. Atrophy and degeneration were important causes for concomitant strabismus. Strabismus patients should have surgical treatment early.
出处
《国际眼科杂志》
CAS
2008年第1期94-96,共3页
International Eye Science
关键词
共同性斜视
眼外肌
病理
concomitant strabismus
extraocular muscle
pathology
