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消化性溃疡患者血前列腺素和血栓素的含量及意义 被引量:7

THE SIGNIFICANCE OF 6 KETO PGF 1α AND THROMBOXANE B2 IN PATIENTS WITH PEPTIC ULCER
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摘要 对29例消化性溃疡和20例正常人的血浆6-酮-PGF1α、TXB2进行了测定。结果表明,溃疡组TXB2含量及TXB2/6-酮-PGF1α比值均明显高于对照组(P<0.01),而6-酮-PGF1α含量和对照组无差异(P>0.05),提示消化性溃疡存在TXA2-PGI2的失衡,其可能参与消化性溃疡的发病。 The contents of 6 Keto PGF1 α and thromboxane B2 (TXB2) in the plasdma of 29 patients with peptic ulcer and 20 normal subjects were measured with radioimmunological assay. The results showed the TXB2 content and TXB2/6 Keto PGF1 α ratio value were significantly higher in patients with peptic ulcer than that in normal subjects. There was no obvious change about 6 Keto PGF1 α content in the two groups. The results suggest that the imbalance of TXB2 PGI2 may be involved the pathogenesis of peptic ulcer.
出处 《中华消化内镜杂志》 1997年第3期166-168,共3页 Chinese Journal of Digestive Endoscopy
关键词 消化性溃疡 前列腺素 血栓素 Peptic ulcer Prostaglandin Thromboxane2
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