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2型糖尿病血清铁蛋白与胰岛功能的关系 被引量:8

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摘要 采用化学发光法测定了107例2型糖尿病组(T2DM)和18例正常对照组(C)的血清铁蛋白(SF)水平,并同时检测了血糖、血脂、胰岛素。采用稳态模式评价胰岛分泌功能(HOMA-β)。结果:T2DM组血清SF明显高于C组(P<0.05)。Spearman相关分析显示,血清SF水平与胰岛β细胞功能之间呈负相关(r=-0.188,P=0.049)。结论:2型糖尿病患者血清SF水平可能与胰岛β细胞功能密切相关。
出处 《实用糖尿病杂志》 2008年第1期19-21,共3页 Journal of Practical Diabetology
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参考文献8

  • 1[1]Kaye TB,Guay AT,Simonson DC.Non-insulin-dependent diabetes mellitus and elevated serum ferritin level.J Diabetes Complications 1993;7(4):246-249.
  • 2吕斌斌,冯静霞,石锦波,王湛国.铁负荷水平与Ⅱ型糖尿病关系研究[J].现代检验医学杂志,2003,18(3):48-49. 被引量:7
  • 3[3]Nolna H,Sakamoto I,Mochizuki H.et al.Relationship between periodontal disease and diabetic retinopathy.Diabetes Care 2004;27(2):615.
  • 4陈肖燕,谢鑫友.1-型糖尿病患者血清铁蛋白测定的临床意义[J].上海医学检验杂志,1999,14(4):230-231. 被引量:2
  • 5[6]Femandez-Real JM,Penarroja G,Castro A,et al.Blood letting in high-fertitin type 2 dmbetes:effects on insulin sensitivity and beta-cell function.Diabetes 2002;51(4):1000-1004.
  • 6[7]Damour.O,Dellamonica C,Vetoer M,et al.Tissue and blood ferritins and isoferritins.Pathol Biol(Paris)1986;34(2):131-143.
  • 7[9]Fernandez-Real JM,Ricart-Engd W,Arroyo E,et al.Serum ferritin as a component of the insulin resistance syndrome.Diabetes Care 1998;21:62.
  • 8[10]Moirand R,Mortaji AM,Loreal O,et al.A new syndrome of liver iron overload with normal transferrin saturation.Lancet 1997;349(9045):95-97.

二级参考文献7

  • 1林其燧 文庆成.临床化学诊断方法大全[M].北京:北京大学出版社,1990.488.
  • 2Heinecke JW, Rosen H, Chair A. Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture[J]. J Clin Invest, 1984, 74:1890.
  • 3Parthasarathy S, Steinberg D, Witztum JL. The role of oxidized low density lipoproteins in the pathogenesis of atheroslerosis[J]. A nnu Rev Med, 1992 '45:219.
  • 4McCord J. Effects of positive iron status at a cellular level[J]. Notr Rev,1996.54:85-88.
  • 5Ford ES,Cogswell ME. Diabetes and serum ferritin concentration among U. S. adults [J]. Diabetes Care, 1999 ; 22: 1978.
  • 6Fernandz-Real JM, Penarroja. Blood letting in high-ferritin type 2 diabetes: effects on insulin sensitivity and beta-cell function[J]. Diabetes, 2002,51:1000.
  • 7Eaton JW,Qian M. Molecular bases of cellular iron toxicity[J]. Free Radic Biol Med, 2002; 32 : 833.

共引文献7

同被引文献57

  • 1张宏,白景文,赵伟,郑凝,董如娇,卫丽君,方佩华.糖尿病大鼠甲状腺组织的超微病理改变[J].天津医药,2006,34(2):108-110. 被引量:40
  • 2张静,刘正娟,孙丽萍,马瑛俨.单纯性肥胖儿童血脂、血清铁蛋白与脂肪肝的关系[J].中国儿童保健杂志,2006,14(3):231-232. 被引量:10
  • 3汪学荣,王飞.生物态补铁剂—血红素铁的研究进展[J].中国食品添加剂,2007,18(3):82-87. 被引量:25
  • 4Vander DL,Grobbee DE,Roest M,et al.Serum ferritin is a risk factor for stroke in postmenopausal women[J].Stroke,2005,36(8):1 637-1 641.
  • 5Swapnil R,Jing M,Joann M,et al.Iron Intake and the Risk of Type 2 Diabetes in Women[J].Diabetes Care,2006,29(6):1 370-1 376.
  • 6Hector FE,Manuel LR,Franciscoar LB,et al.Body Iron Stores Are Increased in Overweight and Obese Women With Polycystic Ovary Syndrome[J].Diabetes Care,2005,28(8):2 042-2 044.
  • 7Megan JM,Jeanne MC,Eliseo G,et al.Serum Ferritin and Risk of the Metabolic Syndrome in U.S.Adults[J].Diabetes Care,2004,27(9):2 422-2 428.
  • 8Michela F,Gaetano R,Guido M,et al.Overexpression of H Ferritin and Up-regulation of Iron RegulatoryProtein Genes during Differentiation of 3T3-L1 Pre-adipocytes[J].J Biol Chem,2000,275(47):36 708-36 712.
  • 9Gabriel QS,Martha LC,Marc JW,et al.Adiponectin Independently Predicts Metabolic Syndrome in Overweight Latino Youth[J].J Clin Endocrinol Metab,2007,92(5):1 809-1 813.
  • 10Alissa EM, Ahmed WH, Al-Ama N ,et al. Relationship between indices of iron status and coronary risk factors including diabetes and the metabolic syndrome in Saudi subjects without overt coronary disease. Trace Elem Med Biol,2007,21:242-254.

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