摘要
目的通过对全身MR弥散加权(全身MR-DWI)和核素骨显像两种技术进行分析对比,评估全身MR-DWI在检测骨转移灶中的作用及其可行性。方法对病理学检查证实为恶性肿瘤并经核素骨显像证实为明确骨转移的20例患者于一周内行全身MR-DWI。将骨骼系统分为7个区域观察:颅骨、胸锁骨、肩胛骨、肋骨、脊柱、骨盆、四肢长骨,以核素骨显像见异常浓聚灶或稀疏灶、MR-DWI见高信号病灶为阳性,分析比较两者所显示的病灶数。结果除脊柱外,其他6个区域MR-DWI所见病灶数均少于核素骨显像,检出率为核素骨显像的59.4%。MR-DWI检出了3处核素骨显像显示阴性的病灶;另有1例核素骨显像呈"超级骨显像",MR-DWI所显示的病灶数明显多于核素骨显像。结论全身MR-DWI对于骨转移灶的诊断有一定意义,与核素骨显像互相补充,可能为临床提供更全面有效的信息。
Objective To compare MR-diffusion weighted imaging（ MR-DWI ） with ^99mTc-MDP whole-body bone scan in terms of efficiency and feasibility of MR-DWI in detection of bone metastasis. Methods Twenty patients with malignant tumors and bone metastasis were enrolled. For each patient, bone scan and MR-DWI were performed within one week. The skeletal system was divided into 7 regions： skull, sternum and clavicle, scapula, ribs, spine, pelvis, limbs. Hot spots as well as cold spots in bone scan images with metastatic characteristics and signals higher than background in MR-DWI were distinguished as metastatic foci. Results Except for the spine, MR-DWI displayed fewer metastatic foci than bone scan images in each of the other 6 skeletal regions. Compared with whole-body bone scan, the detection rate of MR-DWI is 59.4%. However, MR-DWI image displayed metastatic foci in 3 cases although their bone scan images were negative. MR-DWI displayed the metastatic foci clearly in one patient with atypical ＂super scan＂ by bone scintigraphic image. Conclusion MR-DWI has good detection rate, and can act as the supplement of whole-body bone scan in bone metastasis. Combination of bone scan and MR-DWI will increase the detection rate in bone metastasis detection.
出处
《首都医科大学学报》
CAS
2008年第1期19-22,共4页
Journal of Capital Medical University
