摘要
目的评价hPET(hybridPET)与CT及hPET与CT联合应用在支气管肺癌诊断中的价值。方法对192例临床怀疑肺癌的患者在手术前完成hPET及CT2种检查。对肺部病变的18F-FDG浓聚程度及特征进行分析,以局部斑块状放射性异常浓聚灶为阳性(肺癌),以无明显放射性浓聚或浓聚呈云片状、散在性模糊的影像为阴性(良性)。肺部肿块有肺癌CT阳性征象,即认为阳性(肺癌),反之则认为阴性(良性)。结果病理学检测证实145例患者为肺癌,47例为肺部良性病变。hPET假阴性率和假阳性率分别为49.0%和12.1%;CT假阴性率和假阳性率分别为50.9%和9.5%,hPET+CT假阴性率和假阳性率分别为17.8%和7.6%。CT诊断结果与病理学检测结果不符合者41例,占21.4%。在这41例患者中,hPET结果与病理学检测结果符合者24例,占58.5%。单独应用CT者符合率为78.65%,单独应用hPET者符合率为78.13%;CT与hPET联合应用总符合率为91.15%,与前两者相比差异有统计学意义。结论分别单独应用hPET和CT在支气管肺癌诊断的假阴性率和假阳性率之间差异无统计学意义,但二者联合应用可以提高支气管肺癌的诊断准确率。
Objective To evaluate the diagnostic value of hPET and CT in bronchogenic carcinoma and the application of hPET and CT in combination. Methods One hundred and ninety-two inpatients with suspected lung malignancy had hPET and CT examinations which were completed before surgery. All images were analyzed visually. It was considered positive for malignancy if the ,s F- FDG uptake was increased relative to that in the adjacent lung tissue and the uptake of ,s F-FDG was focal. Otherwise, it was considered negative if the mSF-FDG uptake was increased in a sheet form and the margin of the uptake was blurred. If the lung lesions had positive CT signs, they were considered as malignancy. Otherwise, they were considered benign. Results One hundred and forty-five patients were proven to have lung cancer by pathology, and 47 patients had benign lung diseases. The false-negative and false-positive rates of hPET was 49.0% and 12.1%. The false-negative and false-positive of rates CT was 50.9% and 9.5%. The false-negative and false-positive of hPET combination of CT is 17.8% and 7.6%. There were no significant differences between false-positive and false-negative rates of hPET and CT. The CT results of 41 patients（21.4% ） were falsely contrasted with pathological results, but hPET results of 24 patients （58.5%） were identical with pathological results. The coincidence rates of single CT or hPET with pathological results were 78.65% and 78.13%, respectively. The coincidence rate of combined application of hPET and CT with pathological results was 91.15%. Conclusion There are no significant differences of false-positive and false-negative results between single hPET and CT, but combined application of hPET and CT can improve the correct diagnosis rate of lung lesions.
出处
《首都医科大学学报》
CAS
2008年第1期26-28,共3页
Journal of Capital Medical University
