摘要
采用放射免疫法测定缺氧缺血性脑病（ＨＩＥ）新生儿血浆和脑脊液精氨酸加压素（ＡＶＰ）的含量。结果提示：ＨＩＥ时，使ＡＶＰ异常分泌，血浆和脑脊液中ＡＶＰ升高，脑脊液中ＡＶＰ可能参与了ＨＩＥ的病理生理发病机制；并提出生后５天血浆中ＡＶＰ含量可做为判断围产期窒息后脑损伤的指标之一。
Levels of plasma and cerebrospinal fluid (CSF) arginine vasopressin (AVP) in neonates were detected by radioimmunoassay in hypoxic-ischemic encephalopathy (HIE).The results suggested that HIE caused an abnormal release of AVP into plasma and CSF. AVP in CSF played a role in the pathophysiology of HIE. Plasma AVP levels in five days of birth can be considered as an index for cerebral injury induced by perinatal asphyxia.
出处
《河北医科大学学报》
CAS
1997年第4期219-220,共2页
Journal of Hebei Medical University
关键词
缺氧缺血性脑病
精氨酸加压素
新生儿
hypoxic-ischemic encephalopathy
arginine vasopression
plasma
cerebrospinal fluid
etiology
neonate
