摘要
β-内啡肽（β-EP）属于众多内源性阿片肽（EOP）中的一种，研究表明β-EP是重要的镇痛物质，平时仅少量释放入血，在疼痛等应激状态下，血浆中β-EP相应增高。肝癌疼痛时，β-EP不仅通过中枢神经系统起到缓解疼痛的作用，而且在炎症灶局部分泌增多，从而通过外周神经系统发挥作用。因此，研究β-EP的作用机制对治疗肝癌疼痛起重要作用。
Beta-endorphin is a kind of endogenous opioid peptides. It plays a very important role to release pain. Normally,it scarcely can be delivered in blood plasm. But in the condition of pain and stress, the content of beta-endorphin increases obviously in plasma. As the pain happens in liver cancer, beta-endorphin releases the pain by central nervous system. At the same time, it expresses increasingly in inflammation sites to exert effect by peripheral nervous system. Accordingly, researching the mechanism of beta-endorphin has important sense to alleviate the pain of hepatoeellular carcinoma.
出处
《国际肿瘤学杂志》
CAS
2008年第2期140-142,共3页
Journal of International Oncology
关键词
Β内啡肽
癌
肝细胞
疼痛
Beta-endorphin
Careinoma,hepatoeellular
Pain
