摘要
目的研究垂体腺瘤增殖细胞核抗原（ＰＣＮＡ）检测对预测垂体腺瘤术后复发的意义。方法用免疫组织化学ＡＢＣ法检测了２１例复发组和３３例非复发组垂体腺瘤石蜡标本中ＰＣＮＡ的表达。结果ＰＣＮＡ阳性细胞率：复发组第１次手术标本为３８．０４％±５．３０％，第２次手术标本为３６．４２％±４．３０％，非复发组标本为２２．９４％±３．５３％，两组结果差异有显著性（Ｐ＜０．０５）。结论检测ＰＣＮＡ可作为预测垂体腺瘤术后复发的重要指标。
Objective To study the value of PCNA detection in predicting pituitary adenomas recurrence.Method ABC immunohistochemical study of PCNA monoclonal antibody was carried out on paraffin embedded sections of 31 recurrent pituitary adenomas and 33 nonrecurrent adenomas.Result The percentage of cells with nuclei stained was 38.04%±5.30% in initial recurrent adenomas and 36.42%±4.30% in second recurrent adenomad and 22.94%±3.53% in nonrecurrent ones.Statistical analysis showed that the percentage of PCNA positive cells in both initial and second operation of recurrent pituitary adenomas was significantly higher than that in nonrecurrent ones.Conclusion It suggests that the evaluation of the PCNA index assist in predicting the likelihood of pituitary adenoma recurrence. 〖WT5HZ]
出处
《潍坊医学院学报》
1997年第3期172-173,共2页
Acta Academiae Medicinae Weifang
