摘要
本文报告自1992年以来采用自行研制的“自锁式”人工椎体治疗14例脊柱肿瘤合并截瘫病例，其中恶性巨细胞瘤2例，软骨肉瘤1例，恶性纤维组织细胞瘤和纤维肉瘤和血管瘤各1例，骨髓瘤4例，转移瘤4例（肾上腺透明细胞瘤、前列腺癌及肺癌）。采取前方八路切除肿瘤减压后，即用人工椎体重建脊柱的稳定性，术后辅以化疗和放疗，结果满意。术后平均随诊了20．6月（3月～3年8月），随诊时仍存活者10例（占71．3％），其中存活了2年以上5例；死亡病例中，术后平均生存19．8月。患者生活质量均得到明显改善，为脊柱肿瘤治疗提供了又一有效手段。
Objective To evaluate the use of 'self-locking' artificial vertebral prosthesis in surgical treatment for spinal tumor. Methods From 1992 to 1996, 14 cases with spinal tumor and paraplegia were treated with 'self locking' artificial vertebral prosthesis designed by one of the au thors (Ye Qibin) in our department. There were malignant giant cell tumor 2 cases; myeloma 4 cases; metastatic tumor 4 cases and one each with chondrosarcoma, malignant fibrous histocytoma, fibrosarcoma, hemangioma. After radical resection of the tumor and thorough decompression, the vertebral prosthesis was applied to reconstruct the spinal stability. Adjunctive chemotherapy or/and radiotheraphy was given postoperatively. Results At the average followup period of 20. 6 months 10 cases are still alive, 5 of them had survived for more than 2 years.4 cases died with the average survival period of 19. 8 months after oPeration. Almost all the patients obtained the improvement of the quality of the life with relative pain-free and intact neurologic function after operation. Conclusion With 'self-locking'artificial vertebral prosthesis after thorough anterior resection of spinal tumor, it is possible to provide solid internal fixation to re construct the spinal stability.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
1997年第4期288-292,共5页
Acta Academiae Medicinae Sinicae
关键词
人工椎体
脊柱肿瘤
综合疗法
artificial vertebral prosthesis
spinal tumor
