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针刺治疗脑梗死恢复期远期疗效及安全性研究:多中心随机对照 被引量:24

Multi-central controlled study on acupuncture for treatment of cerebral infarction in restoration stage
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摘要 目的:探讨醒脑开窍针刺治疗脑梗死恢复期的远期疗效及安全性。方法:脑梗死恢复期患者234例,以SAS编码,随机分配到醒脑开窍针刺组和常规针刺组(简称醒脑组和常规组)。醒脑组116例,接受醒脑开窍针刺(每日1次,共4周)和西医常规治疗;常规组118例,接受常规针刺和西医常规治疗。随访6个月。主要指标:随访期末生存、治疗和复发情况。次要指标:随访期末神经功能评估,针刺过程中不良事件发生率。结果:6个月随访时醒脑组病死率(0.86%)、继续治疗率(36.21%)与常规组(1.69%、36.44%)差异无显著性意义(X^2=0.29,P=0.59;X^2=0.32,P=0.57),在降低复发率、改善神经功能方面醒脑组优于常规组(P<0.01);2组均未出现严重不良反应。结论:醒脑开窍针刺是安全的,其远期疗效在降低复发率、改善神经功能方面优于常规针刺。 Objective To probe into long-term therapeutic effect and safety of Xingnao Kaiqiao acupuncture for treatment of cerebral infarction in restoration stage. Methods Two hundred and thirty-four cases of cerebral infarction in restoration stage were randomly assigned to a Xingnao group and a routine group. The Xingnao group (n=116) were treated by Xingnao Kaiqiao acupuncture (once each day, for 4 weeks) and routine treatment of western medicine, and the routine group (n= 118) were treated with routine acupuncture and the routine treatment of western medicine. They were followed-up for 6 months. The main indexes living, treatment and recurrence at the end of the following survey and the secondary indexes assessment of nervous functions at the end of the following survey, and the incidence rate of bad events in acupuncture were observed. Results The death rate was 0. 86% and the continuing treatment rate was 36.21% in the Xingnao group, and 1.69% and 36.44% in the routine group, with no significant difference between the two groups (both P〉0.05) at the following-up of 6 months; the Xingnao group in decreasing recurrent rate and improving nervous function was better than the routine group (P〈0.01) ; no severe adverse response was found in the 2 groups. Conclusion Xingnao Kaiqiao acupuncture is safe and it is superior to routine acupuncture in long-term therapeutic effect, decreasing recurrence rate, improving nervous function.
出处 《中国针灸》 CAS CSCD 北大核心 2008年第4期239-243,共5页 Chinese Acupuncture & Moxibustion
基金 国家973项目:2006CB504504 天津市科技攻关重大科技项目:05YFGDSF 02300
关键词 脑梗塞/针灸疗法 醒脑开窍 随机对照试验 治疗结果 随访研究 Brain Infarction/am ther Consciousness Restor Resuscitat Randomized Controlled Trials Treat ment Outcome Follow-Up Studies
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