摘要
目的评价国产腺苷负荷心肌灌注断层显像对心肌缺血的诊断及腺苷试验的安全性。方法60例临床疑似冠心病的患者行腺苷负荷99mTc-MIBI(甲氧基异丁基异腈)心肌灌注断层显像,其中40例行冠脉造影检查。腺苷按0.84mg/kg通过输液泵静脉双通路给药,对心肌灌注显像图作定性分析。结果60例患者行冠脉造影者40例,其中正常8例,1支以上狭窄≥50%者32例,其中病变为单支11例,双支14例,3支7例。60例行腺苷负荷心肌灌注显像检查总阳性率为80%(48/60)。腺苷试验不良反应轻时间短,发生率为80%(48/60)。结论腺苷负荷心肌灌注显像安全可靠。
Objective To evaluate the accuracy and safety of domestic- made adenosine in 99mTc- methoxyisobutylisonitrle （MIBI） myocardial perfusion SPECT/CT during adenosine stress for the diagnosis of myocardial ischemia. Methods Sixty patients with suspected coronary artery disease underwent adenosine stress and rest myocardial perfusion imaging. Adenosine was infused intravenously at a constant rate of 0.14 mg/kg· min for 6 min. At the end of 3 min, 925MBq of 99mTc - MIBI was injected. Results Adenosine stress myocardial perfusion scintigraphy was abnormal in 48 out of the 60 patients. The positive rate was 80%. The frequency of side effects was slight and transient with the incidence of 80% （48/60）. Conclusions The domestic - made adenosine in stress myocardial perfusion imaging is safe and sensitive for detecting myocardial ischemia.
出处
《武警医学》
CAS
2008年第4期323-325,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
冠状动脉疾病
腺苷
SPECT/CT
Coronary artery disease Adenosine Single photon emission computed tomography/CT
