摘要
胃镜取２２１例良性胃病的粘膜组织进行ＨＥ染色，Ｇｅｉｍｓａ染色查Ｈｐ，ＣＥＡ单克隆抗体免疫组化检查。结果：Ｈｐ感染率７７３８％（１７１／２２１），ＣＥＡ阳性率３８９１％（８６／２２１），肠化生（ＩＭ）和／或不典型增生（ＡＨ）发生率２６７％（５９／２２１），在Ｈｐ阳性与阴性病变中，ＩＭ和／或ＡＨ发生率分别为３０４１％（５２／１７１）及１４％（７／５０）（Ｐ＜００５）；ＣＥＡ的阳性率分别为４３２８％（７４／１７１）及２４％（１２／５０）（Ｐ＜００１）。
? The gastric biopsy specimens of 221 patients with benign gastric disorders were used for:HE staining,Geimsa staining to detect Helicobacter pylori(Hp),staining with monoclonal carcinoembryonic antigen(CEA) by the immunohistochemical ABC method.The results reveal that the prevalence of Hp infection was 77.38%(171/221);the positive rate of CEA was 38.91%(86/221);the incidence of intestinal metaplasia(IM) and/or atropical hyperplasia(AH) was 26.7%(59/221);the incidences of IM and/or AH in the lesions with and without Hp infection were 30.41%(52/171) and 14%(7/50)respectively(P<0.05).The CEA positive rates in the lesions with and without Hp infection were 43.28%(74/171) and 24%(12/50) respectively (P<0.01).Our results suggest that Hp infection is related to the high expression of CEA and the occurrence of gastric precancerous lesions.
出处
《胃肠病学和肝病学杂志》
CAS
1997年第2期172-173,共2页
Chinese Journal of Gastroenterology and Hepatology
