摘要
探讨重症监护病房(ICU)患者铜绿假单胞菌分布特征、耐药性及其预防措施。对2006年6月至2007年4月间,浙江温州市中西医结合医院ICU感染患者的临床资料进行分析。在2190例感染患者中,共分离出病原菌960株,革兰阳性菌88株(9.2%),革兰阴性菌746株(77.7%),真菌126(13.1%),其中铜绿假单胞菌296株(30.8%);头孢派酮/舒巴坦仍保持最高抗菌活性,亚胺培南和特治星的耐药率有大幅度上升。ICU铜绿假单胞菌感染耐药现象严重,应注重耐药性监测,控制预防性用药,减少耐药菌株的产生,有针对性地使用抗生素是控制感染的有效措施。
The study was conducted to investigate the distribution and drug resistance of Pseudomonas aeruginosa in Intensive Care Unit （ICU） patients along with the preventive measures. Relevant clinical data of ICU patients in the Traditional Chinese and Western Medicine Hospital in Wenzhou City, Zhejiang province from Jun. 2006 to Apr. 2007 were used for analysis. As a result, a total of 960 strains of pathogens were isolated among the 2190 infected individuals, which comprised 88 strains of gram-positive bacteria （9.2%）, 746 strains of gram-negative bacteria （77.7%） and 126 strains of fungi （13.1%）. The number of strains of Pseudomonas aeruginosa reached 296 （30.8%）. Cefoperazone / sulbactam still maintained the highest antibacterial activity, whereas the resistance to imipenem and Tazocin increased significantly. Surveillance on drug resistance and properly guided administration of preventive medicine to reduce the selection of drug resistant strains are needed given the presence of strongly resistant ICU Pseudomonas aeruginosa. Targeted use of antibiotics is an effective infection control measures.
出处
《疾病监测》
CAS
2008年第3期188-189,共2页
Disease Surveillance
关键词
重症监护病房
铜绿假单胞菌
耐药性
预防
intensive care unit
Pseudomonas aeruginosa
drug resistance
prevention
