摘要
目的:探讨冷冻对胚胎的安全性。方法:回顾性分析2004年1月1日至2006年5月31日在同济医院生殖医学中心行体外受精后,新鲜周期胚胎移植(2160周期)和复苏周期胚胎移植(735周期)的妊娠及妊娠结局,胎儿、新生儿情况及预后。结果:新鲜周期胚胎移植的种植率、临床妊娠率明显高于复苏周期,周期取消率明显低于复苏周期,早期及晚期流产率、活产率、异位妊娠率无明显差异。新鲜周期与复苏周期比较新生儿出生体重、孕周、发育缺陷率、疾病率、胎儿畸形率、死胎率、新生儿期及婴儿期死亡率差异均无显著性。结论:胚胎冷冻技术对部分细胞可能有损伤,但并不增加新生儿发育缺陷率及死亡率。
Objective：To evaluate the safety of frozen-thaw embryos.Methods, The pregnancy rate, pregnancy outcome, information and prognosis of fetal or newbom were retrospectively analyzed in embryos transfer 2160 cases from fresh cycle and 735 cases from reanimate cycle after in vitro fertilization in Reproductive Medical Center of Tongji Hospital. Results. In fresh cycle, the implantation rate and clinical pregnancy rate of embryo transfer obviously higher than in reanimate cycle, but the cycle cancel rate obviously lower. There was no obviously difference about early and late abortion rate, live birth rate, ectopic pregnancy rate in fresh cycle and reanimate cycle. And there is no obviously variance about newborn＇ s birth weight, gestational weeks, newborn developmental defect rate, morbidity rate, fetal anomaly, stillbirth rate, neonatal period and infancy mortality rate between fresh cycle and reanimate cycle. Conclusions. Embryos cryotechnique maybe damage some cells, but it doesn＇t increase newborn development defect rate and death rate.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2008年第3期171-174,共4页
Journal of Practical Obstetrics and Gynecology
关键词
冻融胚胎移植
妊娠
胎儿
新生儿
Frozen-thawed embryos transfer
Pregnancy
Fetal
Newborn
