摘要
目的:提高药品不良反应(ADR)监测水平,为临床合理用药提供参考。方法:对我中心2006年6月～2007年5月收集到的ADR报告810例,就年龄与性别分布、给药途径、药品分类、累及器官或系统、常见ADR症状处理方法和ADR严重程度进行统计分析。结果:810例ADR涉及250个药品品种,抗感染药引起ADR407例,占48.34%;皮肤及其附件损害最多,有437例;新的和严重的ADR42例,占5.19%。结论:ADR的发生与患者的年龄、用药途径、临床用药频率密切相关,应加强严重ADR的监测工作。
OBJECTIVE： To provide references for the improving of the monitoring level of adverse drug reactions （ADR） as well as rational use of drugs in the clinic. METHODS： A total of 810 ADR cases collected in the analysis and evaluation center from June 2006 to May 2007 were analyzed retrospectively and evaluated in respect of distribution of age and sex, route of administration, drug category, organs or systems involved, management of common ADR and the severity of ADR. RESULTS： 250 drugs were involved in the total 810 ADR cases, of whom 407 were induced by anti- infectives （48.34%）, 437 presented with lesions of skin and appendages, 42 （5.19%） were new and severe cases. CONCLUSION： ADR is closely related to patients＇ age and sex, route of administration, and clinical medication frequency. Attention should be paid to the monitoring of severe ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第14期1100-1102,共3页
China Pharmacy
关键词
药品不良反应
因果关系
分析
Adverse drug reactions
Causal relation
Analysis
