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喉癌淋巴结转移相关分子标志物

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摘要 喉癌在头颈部恶性肿瘤中发病率较高,占耳鼻咽喉头颈外科恶性肿瘤的11.6%~22%,占全身肿瘤的2%。复发和转移是导致喉癌死亡率居高不下的主要原因,淋巴结转移是喉癌转移的一个早期事件和独立预后因素。喉癌淋巴结转移过程可能涉及到许多分子作用机制和信号传导途径,包括肿瘤淋巴管生成相关基因、细胞黏附分子、细胞外基因相关蛋白、细胞因子、肿瘤转移相关基因等。本文综述喉癌淋巴结转移的相关分子标志物研究进展。
出处 《国际耳鼻咽喉头颈外科杂志》 2008年第3期163-166,共4页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 喉肿瘤 淋巴转移 肿瘤标记 生物学 LaryngealNeoplasms Lymphatic Metastasis Tumor Markers, Biological
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