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实验兔血管外科手术不同麻醉药物的比较 被引量:7

THE COMPARISON OF DIFFERENT ANESTHESIA APPROACHES FOR VASCULAR SURGERY OPERATION IN RABBITS
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摘要 目的探讨一种简单易行、适用于实验兔血管外科手术的全身麻醉方法。方法选取实验兔96只,随机分为A、B、C、D、E、F六组。A组单纯应用氯胺酮麻醉,B组单纯应用戊巴比妥钠麻醉,C组单纯应用乌来糖麻醉,D组联合应用地西泮和氯胺酮麻醉,E组联合应用地西泮和戊巴比妥钠麻醉,F组联合应用地西泮和乌来糖麻醉。记录六种麻醉方法的麻醉起效时间、麻醉维持时间、麻醉药物用量、动物体温、呼吸频率及麻醉死亡率。结果地西泮和乌来糖复合麻醉起效快、维持时间长、麻醉意外率低、麻醉效果好。结论地西泮和乌来糖复合静脉注射麻醉是一种适用于实验兔血管外科手术的全身麻醉方法。 Objective To explore an appropriate anesthesia for the rabbits in experimental vascular surgery. Methods Ninety-six rabbits were divided into 6 groups randomly and recorded as A,B,C,D,E and F group. The animals in A group were anesthetized by ketamine. The animals in B group were anesthetized by intravenous injection of pentobarbital sodium. The animals in C group were anesthetized by intravenous injection of ethylurethanm. Diazepam and ketamine were used in D group. The animals in E group were anesthetized by diazepam and pentobarbital sodium. Diazepam and ethylurethanm were used in F group. The onset time of anesthesia, anesthetic dosage, animal's temperature, breathing frequency and anesthetic death rate were recorded. Results The combined anesthesia of diazepam and ethylurethanm sustained no less than 240 minutes, and satisfied the rabbits experimental vascular surgery. The combined anesthesia of diazepam and ethylurethanm had the advantage of quick onset, longer anesthetic time, low anesthetic accident rate and excellent anesthetic effect. Conclusion The combined anesthesia of diazepam and ethylulrethanm is an excellent anesthesia for the rabbits experimental vascular surgery.
出处 《河北医科大学学报》 CAS 2008年第3期384-387,共4页 Journal of Hebei Medical University
基金 河北省科技攻关计划项目(编号276101-92)
关键词 麻醉 麻醉药 联用 血管外科手术 anesthesia anesthetics, combined vascular surgical procedures rabbits
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