摘要
目的研究老年男性腰围（WC）、腰臀比（WHR）与临床术后良性前列腺增生（BPH）危险性之间的关系。方法采取以医院为基础的病例对照研究。病例由经组织学检查证实患BPH的男性组成,对照由因患其他疾病入住与病例相同医院的同期病人组成。病例与对照各140例,1∶1匹配。采用标准调查表对全部研究对象进行问卷调查,同时对WC和臀围进行测量。采用多元Logistic回归模型对患者WC、WHR与临床BPH的比值比（OR）及其相应的95%可信区间（CI）进行估计。结果腹型肥胖者（WC〉85cm）与正常WC者（WC≤85cm）相比,发生BPH的OR值为0.98,95%CI0.91-1.33;与正常体型者（WHR〈0.9）相比较,向心性肥胖者（WHR≥0.9）与发生临床BPH的危险性增加有关（OR=1.16,95%CI1.02-1.87,P〈0.05）。结论向心性肥胖为临床BPH的一个危险因素。通过改善饮食习惯和生活方式,保持正常的体型,可有效预防BPH发生。
Objective To examine the association between waist circumference （WC）, waist to hip ratio （WHR） and surgically post-operation benign prostatic hyperplasia （BPH） risk in older men. Methods A hospital-based case control study was conducted. Cases （n = 140） were men with histologically confirmed BPH, and controls （n = 140） were men, admitted to hospital for many different diseases which not related with prostatic conditions. Case and control were matched with 1： 1. Using a standardized structured questionnaire, all subjects were interviewed to measure waist and hip circumference. The odds ratios （OR） and 95% confidence intervals （CI） of BPH for WC and WHR were estimated using unconditional multiple logistic regression models. Results The difference between abdominal obesity males （ WC 〉 85 cm） and those normal waist circumference men （ WC≤85 cm） was not significant （ OR = 0. 98, 95% CI 0. 91 - 1.33 ）. WHR≥ 0.9 was positively related to BPH （compared with WHR〈0.9： OR=1. 16, 95% CI1.02 -1.87, P〈0.05）. Conclusions Obesity, especially central obesity, is an important risk factor for BPH. BPH can be effectively prevented by means of improving diet habit and lifestyle and maintaining normal type of build.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2008年第10期977-979,共3页
Chinese Journal of Gerontology
基金
辽宁省教育厅基金项目(991721591)
关键词
良性前列腺增生
腰围
腰臀比
向心性肥胖
Benign prostatic hyperplasia
Waist circumference
Waist to hip ratio
Central obesity
