摘要
目的统计分析广东省2006年儿童严重药品不良反应报告数据,为确保儿科临床安全、合理用药,减少或避免儿童严重药品不良反应发生提供参考。方法采用回顾性研究方法,对广东省2006年1～12月收集的323例儿童严重药品不良反应报告进行分析。结果本组资料中儿童严重药品不良反应主要为全身性损害;涉及的药物以抗感染药物为主,其中又以头孢菌素类为多;用药途径主要为静脉给药。结论加强儿童严重药品不良反应监测应成为药品安全性再评价研究领域的重点工作之一。
Objective By analyzing the children＇s serious adverse drug reaction（ADR） reports of Guangdong Province in 2006, to provide references for administration and ensure safety use of drug in pediatric clinic. Methods 323 children＇s serious ADR reports collected by Guangdong Center for ADR Monitoring were analyzed using retrospective study methord from January to December 2006. Results The results show that the main type of children＇s serious ADR is systemic damage, more than 1/3 ADR cases induced by antiinfective drugs, and most of them caused by cephalosporins. Intravenous injection is the main way for administration. Conclusion Enhancing the children＇s serious ADR monitoring is one of the important work for our drug safety reevaluation.
出处
《中国药物警戒》
2008年第2期108-113,共6页
Chinese Journal of Pharmacovigilance
关键词
儿童
严重
药品不良反应
分析
children
serious
adverse drug reaction（ADR）
analysis
