摘要
目的探讨定喘汤合参蛤散治疗支气管哮喘的临床效果。方法对轻、中度哮喘患者随机分成二组，一组予定喘汤合参蛤散治疗（治疗组）；另一组每次予氨茶碱（对照组）。观察治疗前后各组哮喘患者的症状评分（根据Chetta A的方法）、血嗜酸细胞计数、血嗜酸性粒细胞阳离子蛋白（ECP，RIA法）、肺功能包括1秒用力呼气量（FEV1）和最大呼气流量（PEF）、蒸馏水激发气道反应性变化试验及不艮反应。结果治疗组在用药二个月后症状评分由治疗前的（6．1±2．3）分降至（2．3±1．6）分（P〈0．01），对照组症状评分由治疗前的（5．8±2．5）分降至（3．3±2．0）分（P〈0．01）：两组患者ECP均有所降低，FEV1、PEF有所提高（P〈0．05），对蒸馏水激发气道反应性均降低，均无明显不艮反应。结论定喘汤合参蛤散对支气管哮喘有明确的治疗作用。
Objective To observe the effect of DCT and SGS in treating Bronchial asthma. Methods Bronchial asthma patients of mild to moderate degree were randomly divided into two groups： the treated group （treated by DCT and SGS） and the control group （treated by Aminophylline）.rhe changes on symptomatic scoring （Chetta＇s method）,pulmonary function （FEV1, PEF）,serum eosinophil count, eosinophil cationic protein （ECP, determined by RIA）, airway response to Ultrasonic nebulized distilled water （UNDW）,and adverse reaction occurred in patients were observed. Results The symptomatic scorings in the treated group and the control group were reduced from 6.1±2.3 and 5.8±2.5 to 2.3±1.6 and 3. 3±2.0 respectively after two months of treatment, ln the two groups ,ECP were reduced ,while FEVI and PEF were improved, UNDW and ECP were reduced ,and no obvious adverse reaction happened. Conclusion DCT and SGS have Good therapeutic effect in treating Bronchial asthma.
出处
《国际医药卫生导报》
2008年第12期102-105,共4页
International Medicine and Health Guidance News
关键词
支气管哮喘
定喘汤
参蛤散
氨茶碱
Bronchial asthma Dingchuan tang Shenge san Aminophylline
