摘要
采用氘代-1-氨基萘作为内标，利用剑桥滤片捕集肯塔基参比卷烟（1R5F、2R4F）烟气，经盐酸超声，二氯甲烷、正己烷萃取，盐酸三甲胺和五氟丙酸酐衍生化，固相萃取仪萃取洗脱纯化后，使用气相色谱-质谱（GC／MS）建立卷烟主流烟气中4种芳香胺化合物的测定方法。4种芳香胺化合物的变异系数均小于5％，回收率在89．8％～106．0％之间，检测限在每支卷烟0．03～0．07ng之间。该方法具有良好的重复性、准确性，适用于卷烟烟气总粒相物中芳香胺的定量分析。
D-1-Naphthylamine as internal standard, four aromatic amines （1-naphthylamine, 2-naphthylamine, 3-aninobiphenyl, 4-aninobiphenyl） in cigarette mainstream smoke were analyzed by GC/MS, through hydrochloric acid ultrasound, methylene dichloride and n- hexane extraction, trimethylamine hydrochloride and pentafluoropropionic anhydride derivation, solid-phase extraction wash and purification process. The RSDs of four aromatic amines are less than 5%, and the recovery are 89.8%-106.0%. The limits of detection of four aromatic amines are 0. 03-0. 07 ng/cig. The method is accuracy, reproducibility and suits for analysis of four aromatic amines.
出处
《质谱学报》
EI
CAS
CSCD
2008年第3期147-152,共6页
Journal of Chinese Mass Spectrometry Society
基金
国家自然科学基金--青年基金项目(No.20701040)
中国烟草总公司郑州烟草研究院院长基金项目
