摘要
目的:调查中国新疆塔吉克族和柯尔克孜族人群线粒体DNACOⅡ/tRNALys基因间小非编码V区串联重复序列9-bp缺失频率。方法:应用PCR及DNA序列分析技术。结果:研究发现,在塔吉克族及柯尔克孜族样本中只发现标准型和缺失型两种多态性,70例柯尔克孜族人群中有2例(2.86%)mtDNA 9 bp缺失;70例塔吉克族人群中有1例(1.43%)mtDNA9-bp缺失。结论:研究结果表明中国新疆塔吉克族和柯尔克孜族人群中存在很少的mtDNA9bp缺失多态性,与其他民族或人种有一定差异。
Objective：To analyze the frequency of 9bp deletion of mtDNA in the ethnic groups of Tajik people and Kirgiz people living in Xinjiang. Method： Polymerase chain reaction was adopted to amplify the frequency of 9bp deletion of mtDNA. Result： The frequency of 9 bp deletion in mtDNA of the ethnic groups in Tajik is 1.43%and in Kirgiz is 2.86% .Conclusion：Research shows that the frequencies of 9 bp deletion in mtDNA in those two ethnic groups in Xinjiang are relatively low, but they are different from those in other people.
出处
《生物技术》
CAS
CSCD
2008年第3期18-20,共3页
Biotechnology
基金
新疆大学生科院与中科院昆明动物研究所合作项目资助("新疆少数民族起源与迁移研究")
新疆大学动物学重点学科项目
关键词
DNA
线粒体
基因缺失
少数民族
DNA
mitochondrial
sequence deletion
minority groups
