摘要
目的:探讨人胃腺癌组织的自体荧光强度及吸收、散射特性.方法:测定28例人胃腺癌标本的肿瘤及非肿瘤区域组织的自体荧光强度及吸收系数光谱和散射系数光谱.结果:人胃腺癌组织自体荧光光谱的峰值明显低于非肿瘤胃壁组织自体荧光光谱峰值并出现双峰;人胃腺癌组织吸收系数在300-720nm光谱范围内明显低于非肿瘤胃壁组织,有显著性差异(P<0.01),散射系数在480-1100nm光谱范围内也明显低于非肿瘤胃壁组织,有显著性差异(P<0.01).结论:人胃腺癌组织的自体荧光强度及吸收、散射特性光谱可有效识别人胃腺癌组织与非肿瘤胃壁组织.
AIM： To investigate the characteristics of autofluorescence, absorption coefficient spectrum and scattering coefficient spectrum for human gastric adenocarcinoma tissues.
METHODS： Twenty-eight samples of human gastric adenocarcinoma taken from tumorous regions and non-tumorous regions were used.Autofluorescence, absorption coefficient and scattering coefficient spectra for gastric wall tissues were measured. RESULTS： Peak value of autofluorescence spectrum for gastric adenocarcinoma was significantly lower than that for non-tumorous gastric wall tissues and double-peak was present. Absorption coefficient for gastric adenocarcinoma tissues with a spectral range of 300-720 nm wavelength, was significantly lower than that for non-tumorous gastric wall tissues （P 〈 0.01）. Scattering coefficient for gastric adenocarcinoma tissues, with a spectral range of 480-1100 nm wavelength, was significantly lower than that for non-tumorous gastric wall tissues （P 〈 0.01）.
CONCLUSION： Autofluorescence, absorption coefficient and scattering coefficient spectra can differentiate gastric adenocarcinoma tissues from non-tumorous gastric wall tissues effectively.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第15期1692-1695,共4页
World Chinese Journal of Digestology
基金
广东省自然科学基金资助项目
No.06032270
广东省医学科学基金资助项目
No.A2006309~~
关键词
胃腺癌
自体荧光
吸收系数
散射系数
Gastric adenocarcinoma
Autofluorescence
Absorption coefficient
Scattering coefficient
