摘要
目的研究踝臂指数(ABI)在下肢外周动脉病患者治疗前后的变化作为评价指标的可行性。方法下肢外周动脉病患者116例,分为2组:A组(单纯药物治疗组)77例,其中男性46例,女性31例,平均年龄(67±8)岁;B组(介入治疗+药物治疗组)39例,其中男性22例,女性17例,平均年龄(65±5)岁。详细记录每一患者的临床资料,包括年龄、性别、身高、体质量、心率、血压、空腹血糖、血脂等。并分别于治疗前、治疗后1个月、治疗后3个月检测ABI。结果①下肢外周动脉病患者治疗前ABI<0.90;②B组治疗后1个月和治疗后3个月的ABI与治疗前相比差异均有统计学意义(P<0.05);③A组治疗后1个月和治疗后3个月的ABI与治疗前相比无明显变化(P>0.05)。结论ABI在下肢外周动脉病患者的治疗中可起重要的指导作用。介入治疗能够及早改善下肢外周动脉病患者的血运,比单纯药物治疗疗效显著。
Objective To study feasibility of ankle arm index for treating patients with peripheral arterial disease. Methods A total of 116 patients with peripheral arterial disease were enrolled,and randomly divided into 2 groups：group A （drug treatment） ,n = 77, male 46 and female 31, mean age （67 ± 8 ） years ; group B （interventional therapy and drug treatment ）, n = 39, male 22 and female 17,mean age （65 ± 5） years. All the patients were tested for ABI by automatic analysis system of angiosclerosis before treatment,1 and 3 month after treatment. Results （1）ABI was 〈 0.90 in patients with peripheral arterial disease before treatment; （2）ABI was increased in patients with peripheral arterial disease after interventional therapy and drug treatment（P 〈 0.05 ） ;（3）ABI was non-increased in patients with peripheral arterial disease after drug treatment （P 〉 0.05）. Conclusion ABI is significant in treatment of patients with peripheral arterial disease. Interventional therapy can improve the blood circulation and the effect is better than simple drug treatment.
出处
《生物医学工程与临床》
CAS
2008年第4期313-315,共3页
Biomedical Engineering and Clinical Medicine
关键词
踝臂指数
下肢外周动脉病
介入治疗
ankle arm index
peripheral arterial disease
interventional therapy
